ENMD-2076 (Tartrate)
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ENMD-2076 (Tartrate)
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CAS No:
1291074-87-7
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Formula:
C21H25N7.x(C4H6O6)
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Chemical Name:
ENMD-2076 (Tartrate)
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Synonyms:
(E)-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine,L-(+)-Tartaric acid;ENMD-2076 (Tartrate);ENMD-2076 L-(+)-Tartaric acid
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CAS No:
Description
ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.
ENMD-2076 (Tartrate) Use and Manufacturing
ENMD-2076 (ENMD-981693, ENMD2076) is a antiangiogenic and Aurora kinase inhibitor with IC50 of 3, 13, 350, 23, 40, 93 and 120 nM for Flt-3, AurA, AurB, Src, KDR/VEGFR2 and FGFR1.
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