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Volasertib

Volasertib structure

CAS No:
755038-65-4
Formula:
C34H50N8O3
Chemical Name:
Volasertib
Synonyms:
Benzamide,N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-;N-[trans-4-[4-(Cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxybenzamide;BI 6727;Volasertib
Categories:
Biochemical Engineering > Inhibitors

Description

Volasertib is a highly potent Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively.

Volasertib Basic Attributes

Molecular Weight：

618.827

Exact Mass：

618.81

EC Number：

-0

Characteristics

PSA：

106

XLogP3：

4.6

Density：

1.3±0.1 g/cm3

Refractive Index：

1.631

Safety Information

Precautionary statement(s)：

P201, P202, P260, P264, P270, P280, P281, P301+P310, P302+P352, P305+P351+P338, P308+P313, P314, P321, P330, P332+P313, P337+P313, P362, P405, P501

Hazard Statements：

H300

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Creative Enzymes Contact Supplier

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CN
4 YRS

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Volasertib (BI 6727) 98%

CAS No.: 755038-65-4

Content: 98%

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