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Ro 4929097

Ro 4929097 structure

CAS No:
847925-91-1
Formula:
C22H20F5N3O3
Chemical Name:
Ro 4929097
Synonyms:
Propanediamide,N1-[(7S)-6,7-dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)-;Propanediamide,N-[(7S)-6,7-dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N′-(2,2,3,3,3-pentafluoropropyl)-;N1-[(7S)-6,7-Dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)propanediamide;Ro 4929097;R0 4929097;RO4929079;2,2-Dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N′-(2,2,3,3,3-pentafluoropropyl)propanediamide
Categories:
Biochemical Engineering > Inhibitors

Description

RO4929097 is a γ secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively.

Molecular Weight：

469.42

Exact Mass：

469.40

EC Number：

-0

HScode：

29242990

PSA：

87.3

XLogP3：

4.6

Density：

1.4±0.1 g/cm3

Boiling Point：

696.3±55.0°C at 760 mmHg

Flash Point：

374.9±31.5 °C

Refractive Index：

1.558

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RO-4929097

CAS No.: 847925-91-1

Content: 99.00%

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