PF-01367338
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PF-01367338
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CAS No:
459868-92-9
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Formula:
C19H18FN3O5P
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Chemical Name:
PF-01367338
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Synonyms:
AG-014699;PF-01367338;AG14699;8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one phosphate;Rucaparib (AG-014699 , PF-01367338);Rucaparib phosphate;AG-014699 (Rucaparib);6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one, 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(MethylaMino)Methyl]phenyl]-, phosphate (1:1)
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CAS No:
Description
Rucaparib (AG-014699, PF-01367338) is a potent and oral PARP1/2/3 inhibitor, with a Ki of 1.4 nM for PARP1 in cell-free assay, also showing binding affinity to eight other PARP domains.
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