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ML-323

ML-323 structure

CAS No:
1572414-83-5
Formula:
C23H24N6
Chemical Name:
ML-323
Synonyms:
ML-323;5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine;4-Pyrimidinamine, 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-;5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamineML323;ML323, >=98%;N-(4-(1H-1,2,3-Triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine
Categories:
Biochemical Engineering > Inhibitors

Description

ML-323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay. The measured inhibition constants of ML-323 for the free enzyme (Ki) is 68 nM.

ML-323 Basic Attributes

Molecular Weight：

384.47686

Exact Mass：

384.206238

HScode：

29299090

Characteristics

PSA：

68.5

XLogP3：

4.6

Density：

1.20±0.1 g/cm3(Predicted)

Boiling Point：

515.4±60.0 °C(Predicted)

Flash Point：

265.5±32.9 °C

Refractive Index：

1.651

Safety Information

Transport codes：

NONH for all modes of transport

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

Computed Properties

Molecular Weight:384.5
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:384.20624479
Monoisotopic Mass:384.20624479
Topological Polar Surface Area:68.5
Heavy Atom Count:29
Complexity:492
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Shaanxi Dideu Medichem Co. Ltd Contact Supplier

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ML-323

CAS No.: 1572414-83-5

Grade: Industrial Grade

Content: 99%

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