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Masitinib

Masitinib structure

CAS No:
790299-79-5
Formula:
C28H30N6OS
Chemical Name:
Masitinib
Synonyms:
Benzamide,4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide;Masitinib;Masiviera;Masican
Categories:
Biochemical Engineering > Inhibitors

Description

Masitinib is an orally available Kit inhibitor with an IC50 of 200 nM. It also inhibits PDGFRα/β with an IC50 of 540 nM/800 nM nM.

Molecular Weight：

498.64

Exact Mass：

498.64

PSA：

102

XLogP3：

2.88

Density：

1.3±0.1 g/cm3

Melting Point：

90-95°C

Refractive Index：

1.682

Storage Conditions：

Refrigerator

Masitinib controlled-release implant for treating solid neoplasm.

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