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Naringin dihydrochalcone

Naringin dihydrochalcone structure

CAS No:
18916-17-1
Formula:
C27H34O14
Chemical Name:
Naringin dihydrochalcone
Synonyms:
1-Propanone,1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-;Glucopyranoside,3,5-dihydroxy-4-(p-hydroxyhydrocinnamoyl)phenyl 2-O-(6-deoxy-α-L-mannopyranosyl)-,β-D-;Phloretin,4′-(2-O-α-L-rhamno-β-D-glucopyranoside);1-[4-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone;Naringin dihydrochalcone
Categories:
Biochemical Engineering > Biosynthetic Natural Products

Description

Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

White solid, Bland aroma

Naringin dihydrochalcone Basic Attributes

Molecular Weight：

582.55

Exact Mass：

582.55

EC Number：

700-320-7|606-166-6

UNII：

7233QDO0QW

HScode：

29329990

Characteristics

PSA：

236.06000

XLogP3：

0.25340

Appearance：

White to Off-white Powder

Density：

1.63±0.1 g/cm3(Predicted)

Melting Point：

168-169 °C

Boiling Point：

916.8±65.0 °C(Predicted)

Flash Point：

302.7±27.8 °C

Refractive Index：

1.696

Water Solubility：

Soluble in DMSO

Vapor Pressure：

0mmHg at 25°C

Safety Information

wgk germany：

hazard class code：

R36/37/38:Irritating to eyes, respiratory system and skin .

safety instructions：

S26-S36

Marks：

GHS Classification：

Not Classified

Drug Information

MeSH Entry Terms：

4',5,7-trihydroxyflavanone 7-rhamnoglucoside

Naringin dihydrochalcone Use and Manufacturing

Methods of Manufacturing

Natural extract 120g 600g8percent naringin was dissolved in a solution of potassiumhydroxide, clear solution was filtered, and the filtrate was added 2000ml autoclave, 200g of ethanol was added, 3g palladium on carbon catalyst, 55 introducing hydrogenat a pressure of 1 ~ 2MPa , 5 ~ 7H after hydrogen absorption substantially completehydrogen absorption, the reaction solution was taken out, filtered off and palladium oncarbon, hydrogenation was directly acidified with hydrochloric acid to adjust pH to 5-7, stirred sufficiently crystallized white solid precipitated quickly. Cooling to 20 filtration, the wet product was dried under reduced pressure at 60 , you can getdihydro naringin chalcone 118g, white powder, liquid purity 98.9percent molar yield of 98percent.Products from light nitrogen stored in a cool place.

Use Classification：

Food additives -> Flavoring Agents|Flavoring Agents -> JECFA Flavorings Index

Food Additive Classes：

Flavoring Agents

Computed Properties

Molecular Weight:582.5
XLogP3:-0.3
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:9
Exact Mass:582.19485575
Monoisotopic Mass:582.19485575
Topological Polar Surface Area:236
Heavy Atom Count:41
Complexity:827
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Naringin dihydrochalcone

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CN
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Naringin dihydrochalcone 98% supplier Plant extract Pharmaceutical made in china

CAS No.: 18916-17-1

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Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
2 YRS

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Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

Factory price and higher quality Naringin dihydrochalcone cas 18916-17-1

CAS No.: 18916-17-1

Grade: Pharmaceutical Grade

Content: 0%

Inquiry
Benepure Pharmaceutical Co., Ltd. Contact Supplier

CN
9 YRS

Business licensed Certified factory

Manufactory Supplier of Neohesperidin Dihydrochalcone,Baicalin,Cephalotaxine,Diosmin,Naringin,Cranberry Extract,Blueberry Extract,Quercetin Dihydrate,Black Currant Extract,Soybean Isoflavones,Bilberry Extract,Rutin,Luo Han Guo Extract,Hesperidin,Oleanolic Acid,Grape Seed Extract,Halquinol,Troxerutin,Water Soluble Citrus Bioflavonoids,Hesperidin Methylchalcone,Amino Acids and Their Derivatives,Esculine,Stevia Leaf Extract,Citrus Polymethoxy Flavones (PMFs),Pine Bark Extract,L-rhamnose Monahydrate,Quercetin Anhydrous,Milk Thistle Extract,Resveratrol (Vitis vinifera L.),Hidrosmin,Resveratrol (Polygonum Cuspidatum),St.John's Wort Extract

Naringin Dihydrochalcone

CAS No.: 18916-17-1

Grade: Food Grade

Content: 98%

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Guide of Naringin dihydrochalcone

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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Naringin dihydrochalcone

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