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Elastins

Elastins structure

Elastins 

structure
  • CAS No:

    9007-58-3

  • Chemical Name:

    Elastins

  • Synonyms:

    Elastins;Elastin;E 91 (elastin);E 91;Elastin E60;Bovine Aortic Elastin SB87;9050-20-8

  • Categories:

    Cosmetic Ingredient  >  Skin Conditioning

Description

A fibrous protein that is themajor constituent of the yellow elasticfibres of connective tissue. It isrich in glycine, alanine, proline, andother nonpolar amino acids that arecross-linked, making the protein relativelyinsoluble. Elastic fibres canstretch to several times their lengthand then return to their original size.Elastin is particularly abundant inelastic cartilage, blood-vessel walls,ligaments, and the heart.


N-Acetyl-L-leucyl-L-isoleucylglycyl-L-valyl-N-methyl-L-prolinamide is an oligopeptide.

Elastins Basic Attributes

552.70662

552.36400

232-701-4

Characteristics

166

4.20150

powder

1.126g/cm3

916.6ºC at 760mmHg

508.2ºC

1.508

H2O: soluble

2-8°C

Safety Information

NONH for all modes of transport

3

22-24/25

B

Drug Information

alpha Elastin

Elastins Use and Manufacturing

Uses

elastin (hydrolyzed) is a modified form of elastin that has better solubility, and thus is more convenient for use in cosmetic formulations than regular elastin. elastin is a surface protective agent used in cosmetics to alleviate the effects of dry skin, enhance skin flexibility, improve skin feel, increase and improve the tension of the skin, and influence the formation of tropocollagen fibers when used in combination with soluble collagen. Preparations containing elastin and peptides derived from it are reported to promote wound healing. Reportedly, in such systems, elastin can absorb lipids from the skin, and when applied to scars, increase the structural glycoproteins and elastin available in the scar tissue. elastin is an elastic structural protein found in the dermis together with collagen, and is difficult to obtain in pure form. Collagen and elastin are similar, although elastin has a different amino acid composition and is found in lower concentrations. Its molecular size is also much smaller than collagen’s, and as a result, there is a tendency to believe that it penetrates the surface epidermal layers, thereby improving overall skin appearance, softness, and suppleness. elastin is often used in moisturizing products and those products for aging or mature skin.

Cosmetics -> Skin conditioning; Smoothing

Computed Properties

Molecular Weight:552.7
XLogP3:0.1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:14
Exact Mass:552.36353327
Monoisotopic Mass:552.36353327
Topological Polar Surface Area:166
Heavy Atom Count:39
Complexity:892
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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