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Neobavaisoflavone

Neobavaisoflavone structure

Neobavaisoflavone 

structure
  • CAS No:

    41060-15-5

  • Formula:

    C20H18O4

  • Chemical Name:

    Neobavaisoflavone

  • Synonyms:

    4H-1-Benzopyran-4-one,7-hydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-;4H-1-Benzopyran-4-one,7-hydroxy-3-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-;7-Hydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-4H-1-benzopyran-4-one;Neobavaisoflavone

  • Categories:

    Natural Products  >  Flavonoids

Description

Neobavaisoflavone, an isoflavone isolated from Psoralea corylifolia, has striking anti-inflammatory and anti-cancer effects. IC50 value: 42.93 μM (toward CCRF-CEM cells); 114.64 μM [against HCT116 (p53(+/+)) cells] [2]Target:In vitro: In the cancer cells, neobavaisoflavone sensitizes human U373MG glioma cells to TRAIL-mediated apoptosis; upregulated DR5 expression; induced TRAIL-mediated apoptosis in human glioma cells by suppressing migration and invasion, and by inhibiting anoikis resi

Neobavaisoflavone Basic Attributes

322.36

322.35

Characteristics

66.8

4.4

1.3±0.1 g/cm3

189-191 °C

197.7±23.6 °C

1.645

Safety Information

NONH for all modes of transport

DJ3100028

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