(+)-Laurolitsine
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(+)-Laurolitsine
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CAS No:
5890-18-6
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Formula:
C18H19NO4
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Chemical Name:
(+)-Laurolitsine
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Synonyms:
4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-,(6aS)-;Laurolitsine;Norboldine;6aα-Noraporphine-2,9-diol,1,10-dimethoxy-;4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-,(S)-;(6aS)-5,6,6a,7-Tetrahydro-1,10-dimethoxy-4H-dibenzo[de,g]quinoline-2,9-diol;(+)-Norboldine;(+)-Laurolitsine
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CAS No:
Description
Laurolitsine ((+)-Norboldine) is an alkaloid isolated from the leaves of Peumus boldus Molina[1].
Laurolistine is an aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is a member of phenols, an aromatic ether and an aporphine alkaloid. It derives from an aporphine.
Computed Properties
Molecular Weight:313.3
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:313.13140809
Monoisotopic Mass:313.13140809
Topological Polar Surface Area:71
Heavy Atom Count:23
Complexity:433
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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