Propetamphos

Propetamphos technical is a yellowish, oily liquid at room temperature and a moderately toxic acaricide and insecticide. It is sparingly soluble in water, but very soluble in acetone, chloroform, ethanol, and hexane. The US EPA has classifi ed propetamphos as a GUP and RUP, indicating that its handling should be done by certifi ed, qualifi ed applicators. Propetamphos is used for the control of cockroaches, fl ies, ants, ticks, moths, fl eas, and mosquitoes in households and where vector eradic

In the presence of a catalyst and an acid-binding agent, the intermediate obtained from the reaction of isopropyl 3-hydroxybutenoate with thiophosphoryl chloride is then condensed with methanol and ethylamine to produce dimethoate. In industrial production, add tributylamine to the mixture of isopropyl acetoacetate and thiophosphoryl chloride. Stir and cool at -3°C when feeding, continue to stir at 0-3°C for 4.5h, separate the viscous oily liquid, add toluene, Petroleum ether, filtered off tributylammonium chloride, the filtrate was concentrated in vacuo at a bath temperature of 30 ℃, methanol was added to the residue, as quickly as possible to 0 ℃, stirred for 4h, then add 70% ethylamine in water, feed Temperature -5℃, mix at 0℃ and stir for 4.5h. The reaction mixture was extracted twice with about 10% hydrochloric acid solution. Petroleum ether was added during the second extraction to facilitate extraction. The petroleum ether was washed with water and alkali, dried over anhydrous sodium sulfate, and the solvent was removed to obtain methoprene. Raw material consumption quota: 670kg/t of tributylamine, 520kg/t of isopropyl acetoacetate, 650kg/t of thiophosphoryl chloride, 470kg/t of methanol, and 820kg/t of ethylamine (70%).

Insecticide.