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Phosphamidon

Phosphamidon structure

CAS No:
13171-21-6
Formula:
C10H19ClNO5P
Chemical Name:
Phosphamidon
Synonyms:
Phosphoric acid,2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propen-1-yl dimethyl ester;Phosphoric acid,dimethyl ester,ester with 2-chloro-N,N-diethyl-3-hydroxycrotonamide;Phosphoric acid,2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl ester;Dimecron;Phosphamidon;Dimecron 50;Dimecron 100;O,O-Dimethyl-O-1-chloro-1-N-diethyl-carbamoyl-1-propen-2-yl phosphate;Dimecron 20;Phosphamidone;Sundaram 1975;Merkon;Kinadan;Kinadon plus
Categories:
Agrochemicals > Insecticides

Description

Phosphamidon is a pale yellow to colorless oily liquid with a faint odor. It is miscible with water and is soluble in aromatic hydrocarbons. Phosphamidon decomposes on heating and releases highly toxic fumes, such as phosphorus oxides, hydrogen chloride, and nitrogen oxides. It reacts with bases (hydrolysis) and attacks metals such as iron, tin, and aluminium. Phosphamidon should be handled by trained personnel wearing protective clothing. Phosphamidon is used as a broad-spectrum insectici

Phosphamidon Basic Attributes

Molecular Weight：

299.69

Exact Mass：

299.69

EC Number：

236-116-5

HScode：

29241200

Characteristics

PSA：

74.88000

XLogP3：

0.86

Density：

1.2132 g/cm³ @ Temp: 25 °C

Melting Point：

-45 °C

Boiling Point：

162 °C @ Press: 1.5 Torr

Flash Point：

169.1±27.9 °C

Refractive Index：

1.4718 (589.3 nm 25℃)

Water Solubility：

Totally miscibleWater soluble . Hydrolyzed by alkali with a half-life at 73°F of 13.8 days at pH 7 and 2.2 days at pH 10 .

Storage Conditions：

2-8°C

Vapor Pressure：

2.2×10 -3 Pa (25 °C)

Toxicity：

Oral-rat LD50: 8 mg/kg; Oral-Mouse LD50: 6 mg/kg

Flammability characteristics：

Open flame is flammable; heat releases toxic nitrogen oxide, sulfur oxide, phosphorus oxide, chloride gas

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

3018

wgk germany：

hazard class code：

24-28-50/53-68

safety instructions：

23-36/37-45-60-61

RTECS Number：

TC2800000

Marks：

T+,N

Storage features：

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Precautionary statement(s)：

P264-P273-P280-P301 + P310-P312-P501

Hazard Statements：

H300-H311-H341-H410

Toxicity

Toxicity class：

most toxic

Phosphamidon Use and Manufacturing

Methods of Manufacturing

Put diethylamine into the reaction pot, stir, add diketene dropwise at 40-45 ℃, add it, and react for 1h to obtain diethylacetylacetamide. Add diethyl acetylacetamide to the chlorination pot, pass chlorine gas at 40-50 ℃ to react until the density of the chlorinated liquid reaches 1.208-1.210, which is the chlorine point. Wash the chloride with 3-5% sodium hydroxide solution until pH=6, dehydrate under reduced pressure, and control the water content at 0.02% to obtain chloride. Then, the chloride is heated to 85-95°C, and trimethyl phosphite is added (the molar ratio is chloride: trimethyl phosphite = 1: 1.07). After the addition is completed, the heat-preservation reflux is performed for 5 hours to condense the crude phosphoramidite.

Uses

Insecticide.

Computed Properties

Molecular Weight:299.69
XLogP3:1.3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:299.0689374
Monoisotopic Mass:299.0689374
Topological Polar Surface Area:65.1
Heavy Atom Count:18
Complexity:359
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes