2,6-Difluorobenzoyl isocyanate

white crystalline solid

The preparation method is that 2, 6-difluorobenzamide reacts with oxalyl chloride to obtain the corresponding isocyanate. Add 2, 6-difluorobenzamide and solvent into the enamel reaction kettle, add oxalyl chloride dropwise under stirring, when the quantitative oxalyl chloride is added dropwise, heat up and remove the solvent to obtain 2, 6-difluorobenzene Formyl isocyanate.

2,6-Difluorobenzoyl isocyanate is an important intermediate in the synthesis of benzoyl urea pesticides, and can be used to synthesize almost all varieties of benzoyl urea insecticides, such as hexaflumuron and insecticides. Urea, flumicarbazone, fipronil, diflubenzuron, flufenuron, lufenuron, flufenuron, flufenuron, etc.

Molecular Weight:183.11
XLogP3:2.7
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:183.01318466
Monoisotopic Mass:183.01318466
Topological Polar Surface Area:46.5
Heavy Atom Count:13
Complexity:241
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes