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Oxalyl chloride

Oxalyl chloride structure

Oxalyl chloride 

structure
  • CAS No:

    79-37-8

  • Formula:

    C2Cl2O2

  • Chemical Name:

    Oxalyl chloride

  • Synonyms:

    Ethanedioyl dichloride;Oxalyl chloride;Oxalic acid dichloride;Oxaloyl chloride;Oxalyl dichloride;Oxalic dichloride;Ethanedioyl chloride;Oxalic acid chloride;Oxaloyl dichloride;Dichlorooxalic acid

  • Categories:

    Agrochemicals  >  Pesticide Intermediates

Description

Oxalyl Chloride, a distinct presence in the chemical world, is marked by the formula C₂Cl₂O₂, a colorless liquid with a strong, pungent odor that is hard to ignore. The smell, as it were, was a wordless declaration in the chemistry laboratory of its extraordinary status as an important organic compound. In the vast arena of chemistry, Oxalyl Chloride undoubtedly plays a pivotal role. It is not only unique because of its unique molecular structure - two chlorine atoms are like wings, firmly guarding the two carboxyl groups in the center, but also because of its excellent reactivity and is favored. This reactivity, like a versatile artist, is able to have an intimate ""dialogue"" with a variety of substances, such as water, alcohol, and amines, thereby creating a rich variety of chemical products. When Oxalyl Chloride meets water, a violent chemical reaction begins. In this process, the carboxyl groups of Oxalyl Chloride are attracted to the hydrogen and hydroxyl groups of the water molecules, resulting in carboxylic acids and hydrogen chloride. This process not only shows the deep ""friendship"" between Oxalyl Chloride and water, but also reveals the mystery of acid-base neutralization in chemical reactions. Oxalyl Chloride and the reaction of the alcohol, like a skilled craftsman, in the fine operation of the alcohol into esters. Ester compounds, with their unique aroma and wide range of applications, have become an indispensable part of the chemical industry. The reaction of Oxalyl Chloride with alcohols not only enriches the variety of chemicals, but also brings more color and possibilities to our lives. Oxalyl Chloride reacts with amines to form amino compounds. This process not only shows the diversity of Oxalyl Chloride, but also reveals the complex interactions between organic compounds. As an important organic compound, amino compounds are widely used in medicine, pesticides, dyes and other fields. The reaction of Oxalyl Chloride with amines has undoubtedly provided us with a powerful tool and support to explore these fields. It is worth noting that the strong pungent smell of Oxalyl Chloride not only reminds us to be careful when using it, but also leads us to think deeply about chemical safety. While enjoying the convenience and fun brought by chemistry, we should always pay attention to chemical safety to ensure the safety of our lives and property.

Oxalyl chloride Basic Attributes

126.93

126.93

1361988

201-200-2

R4Y96317DW

DTXSID3058822

29171990

Characteristics

34.1

1.08

APHA: 0-150 Liquid

1.6±0.1 g/cm3

-16 °C

63.5 °C

176-178°C

1.449

Solubility in water: reaction

StoreCold

150 mm Hg ( 20 °C)

4.4 (vs air)

Safety Information

II

8

UN 2927 6.1/PG 2

2

14-20-29-34-40-23/24/25-37-35-23

26-36/37/39-43-45-8-24/25-23-27

KI2950000

C,T

Toxic/Corrosive/Store Cold/Lacrymatory

Stable. Incompatible with bases, alcohols, steel, oxidizing agents, alkali metals. Moisture sensitive. Reacts violently with water, liberating toxic gas.

P261-P280-P305 + P351 + P338-P310

H314-H332-H335-H336-H351-H373

|Danger|H260 (72.16%): In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases]|P223, P231+P232, P260, P261, P264, P270, P271, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P312, P321, P330, P335+P334, P363, P370+P378, P402+P404, P403+P233, P405, and P501|Aggregated GHS information provided by 431 companies from 33 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

oxalyl chloride

Oxalyl chloride Use and Manufacturing

Methods of Manufacturing

The preparation method is obtained by reacting oxalic acid with phosphorus pentachloride to obtain oxalyl chloride. The reaction equation is shown in the figure. After mixing phosphorus pentachloride with anhydrous oxalic acid, it is slowly heated to about 64°C, and the reaction is performed until almost no hydrogen chloride is released. The crude product obtained is then rectified to obtain oxalyl chloride.

Uses

Oxalyl Chloride, one of the most prominent compounds in chemistry, has a wide range of applications in the organic synthesis and pharmaceutical industry. As an indispensable ""chemical magician"", Oxalyl Chloride with its unique chlorination and dehydration ability, in the construction of complex organic molecular structures shine on the stage. Oxalyl Chloride is a skillful craftsman in the vast field of organic synthesis, skillfully participating in and facilitating the occurrence of many key reactions. It not only acts as a chlorination agent, it can efficiently convert functional groups such as alcohols and amines into corresponding chlorides, which are often important intermediates for the synthesis of more complex organic molecules. Oxalyl Chloride also exhibits excellent dehydrating properties, enabling anhydrides, amides and other compounds to form more stable structures through dehydration reactions, which is especially important for the synthesis of specific organic molecules. In the pharmaceutical industry, Oxalyl Chloride plays a pivotal role. In the synthesis process of drug molecules, it often acts as a ""bridge"" connecting different chemical fragments, helping scientists to build a drug molecule with a specific biological activity. From antibiotics to anticancer drugs, from analgesics to antidepressants, Oxalyl Chloride's participation in the synthesis of these drugs makes it possible to contribute to human health and indelible power. In addition to the above applications, Oxalyl Chloride is an important raw material for the preparation of oxalic acid and its derivatives. Through a series of carefully designed chemical reactions, Oxalyl Chloride can be converted into oxalic acid, oxalates and other compounds, which have a wide range of applications in food, chemical, medicine and other fields. For example, oxalic acid is widely used as a food additive and cleaning agent; Oxalates are used in the precipitation and separation of metal ions due to their unique chemical properties. In the field of agricultural chemistry, Oxalyl Chloride also shows its unique value. As a pesticide intermediate, it provides strong support for the manufacture of efficient and environmentally friendly plant protection agents. By taking part in the synthesis of pesticide molecules, Oxalyl Chloride helps scientists design new pesticides that can accurately attack pests and diseases, while reducing the damage to the environment and crops. The wide application of these pesticides not only improves the yield and quality of crops, but also effectively guarantees the sustainable development of agricultural production. However, it is worth noting that Oxalyl Chloride, as a highly reactive compound, must comply with strict safety procedures during use. Because it is easy to react violently with water, alcohol and other active hydrogen compounds and release toxic gases (such as hydrogen chloride), strict protective measures must be taken during use and storage to prevent accidents. This includes but is not limited to wearing personal protective equipment such as protective glasses, protective clothing and respirators; And ensure that the operation area is well ventilated, away from fire sources and other safety measures.

Production

100,000 - 500,000 lb

All other basic organic chemical manufacturing|Ethanedioyl dichloride: ACTIVE

Computed Properties

Molecular Weight:126.92
XLogP3:1.7
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:125.9275346
Monoisotopic Mass:125.9275346
Topological Polar Surface Area:34.1
Heavy Atom Count:6
Complexity:75.5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Price Analysis

Make your Oxalyl chloride purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Oxalyl chloride prices .
  • Data: 2026-07-29
  • Price: 29500.00Yuan/ton
  • Change: 0

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