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Diclomezine

Diclomezine structure

CAS No:
62865-36-5
Formula:
C11H8Cl2N2O
Chemical Name:
Diclomezine
Synonyms:
3(2H)-Pyridazinone,6-(3,5-dichloro-4-methylphenyl)-;6-(3,5-Dichloro-4-methylphenyl)-3(2H)-pyridazinone;Diclomezine;Monguard;109675-63-0;1135442-72-6
Categories:
Agrochemicals > Fungicides

Description

ChEBI: A pyridazinone that is pyridazin-3(2H)-one which is substituted at position 6 by a 3,5-dichloro-4-methylphenyl group. A fugicide, it is used to treat rice sheath blight caused by Rhizoctonia solani.

Diclomezine is a pyridazinone that is pyridazin-3(2H)-one which is substituted at position 6 by a 3,5-dichloro-4-methylphenyl group. A fugicide, it is used to treat rice sheath blight caused by Rhizoctonia solani. It has a role as an antifungal agrochemical. It is a dichlorobenzene and a pyridazinone.

Diclomezine Basic Attributes

Molecular Weight：

255.1

Exact Mass：

255.10

UNII：

UNB23N8AVX

DSSTox ID：

DTXSID0058146

HScode：

2933990013

Characteristics

PSA：

41.5

XLogP3：

3.05210

Density：

1.44 g/cm3

Melting Point：

251.5 °C

Refractive Index：

1.643

Water Solubility：

2.90e-06 M

Storage Conditions：

0-6°C

Safety Information

hazard class code：

safety instructions：

Marks：

Precautionary statement(s)：

P261, P271, P304+P340, P311, P321, P403+P233, P405, P501

Hazard Statements：

H331

GHS Classification：

|Danger|H331 (100%): Toxic if inhaled [Danger Acute toxicity, inhalation]|P261, P271, P304+P340, P311, P321, P403+P233, P405, and P501|Aggregated GHS information provided by 128 companies from 1 notifications to the ECHA C&L Inventory.

Diclomezine Use and Manufacturing

Methods of Manufacturing

Succinic anhydride and toluene undergo Friedel-Crafts reaction, and then chlorinated at low temperature to generate 4-methyl-3, 5-dichlorobenzoylpropionic acid, and then chlorinated at 50°C so that the hydrogen atom on the carbonyl carbon atom is replaced by chlorine. Finally, it reacts with hydrazine to generate pyridalonil.

Uses

A new pesticide fungicide is highly effective against rice sheath blight.

Computed Properties

Molecular Weight:255.10
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:254.0013683
Monoisotopic Mass:254.0013683
Topological Polar Surface Area:41.5
Heavy Atom Count:16
Complexity:342
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Succinic anhydride

Chlorobenzene