 Home > Encyclopedia > Methyl isothiocyanate

Methyl isothiocyanate

Methyl isothiocyanate structure

CAS No:
556-61-6
Formula:
C2H3NS
Chemical Name:
Methyl isothiocyanate
Synonyms:
Methane,isothiocyanato-;Isothiocyanic acid,methyl ester;Isothiocyanatomethane;WN 12;Methyl isothiocyanate;Methyl mustard oil;Morton EP-161E;Trapex;Trapexide;Tropex;Methyl thioisocyanate;Methyl mustard;MIT;Methyl isothiocyanide;MIT (pesticide);Trapex (soil fumigant);Capparin;Isothocyanatomethane;1800084-95-0
Categories:
Agrochemicals > Fungicides

Description

colourless solid Methyl isothiocyanate is a crystalline solid. Horseradish, acrid odor. Colorless to tan liquid; pungent, penetrating, mustard-like odor.

Methyl isothiocyanate Basic Attributes

Molecular Weight：

73.12

Exact Mass：

73.12

BRN：

605319

EC Number：

209-132-5

HScode：

29309090

Characteristics

PSA：

44.4

XLogP3：

0.94

Appearance：

White to pale yellow Low Melting Solid

Density：

1.0691 g/cm³ @ Temp: 37 °C

Melting Point：

36 °C

Boiling Point：

119 °C

Flash Point：

90 °F

Refractive Index：

1.488

Water Solubility：

H2O: 7.6 g/L;slightly soluble

Storage Conditions：

2-8°C

Vapor Pressure：

21 mm Hg ( 20 °C)

Vapor Density：

2.53 (Air = 1)

Toxicity：

Oral-rat LD50: 72 mg/kg; Oral-Mouse LD50: 90 mg/kg

Flammability characteristics：

Flammable; heat decomposes toxic cyanide and sulfide

Explosive limit：

Product vapor forms explosive mixtures with air; prevent build-up of electrostatic charges, sparks, and open flame. /MITC-Fume/

Odor：

Horseradish-like odor

Safety Information

Packing level：

Hazard category：

6.1

Transport codes：

UN 2477 6.1/PG 1

wgk germany：

hazard class code：

23/25-34-43-50/53

safety instructions：

36/37-38-45-60-61

RTECS Number：

PA9625000

Marks：

T,N

Storage features：

Treasury is ventilated, low temperature and dry; stored and transported separately from oxidant

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, alcohols, strong bases, amines.

Precautionary statement(s)：

P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233

Hazard Statements：

H301 + H331-H310-H314-H317-H410

Toxicity

Toxicity class：

highly toxic

Methyl isothiocyanate Use and Manufacturing

Methods of Manufacturing

Using monomethylamine, carbon disulfide and ethyl chloroformate as raw materials, it is prepared through the following steps. The carbon disulfide and sodium hydroxide solution were mixed and cooled to 10-15°C, and a 35% methylamine aqueous solution was added within 0.5h. Warm stirring for 1-2h to complete the reaction and produce a bright red solution. It was cooled to 35-40°C, and ethyl chloroformate was added dropwise with stirring. After the addition, stirring was continued for 30 min, and the temperature was lowered to about 30°C. The upper layer isothiocyanate is separated, dried with anhydrous sodium sulfate, and then fractionated, and the fraction collected at 115-121°C is the finished product. The yield is about 70%.

Uses

Pesticide; soil fumigant.

Computed Properties

Molecular Weight:73.12
XLogP3:0.9
Hydrogen Bond Acceptor Count:2
Exact Mass:72.99862027
Monoisotopic Mass:72.99862027
Topological Polar Surface Area:44.4
Heavy Atom Count:4
Complexity:44
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Methyl isothiocyanate

Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

Methyl isothiocyanate

CAS No.: 556-61-6

Grade: industrial Grade

Content: 98%

Inquiry
JHECHEM CO LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of BBiochemicals,Peptides,Silicones,Pharmaceuticals,Building blocks,Intermediates

Methyl isothiocyanate

CAS No.: 556-61-6

Grade: Industrial Grade

Content: 99%

Inquiry