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Home > Encyclopedia > CARBOXYMETHYLCELLULOSE CALCIUM

CARBOXYMETHYLCELLULOSE CALCIUM

pharmaceutical raw materials
CARBOXYMETHYLCELLULOSE CALCIUM structure

CARBOXYMETHYLCELLULOSE CALCIUM 

structure
  • CAS No:

    9050-04-8

  • Formula:

    C23H30ClN3O

  • Chemical Name:

    CARBOXYMETHYLCELLULOSE CALCIUM

  • Synonyms:

    Cellulose,ethers,carboxymethyl ether,calcium salt;N4-(2-Chloro-7-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine;hylon600;CMCCalcium;CALCIUMCARBOXYLMETHYLCELLULOSE;Calciam carboxymethylceUulose;Carboxymethylcellulose calcium (nf);Carmellose calcium (jp15)

  • Categories:

    Cosmetic Ingredient  >  Film Forming

Description

DS 0.5-0.7 Carboxymethylcellulose calcium occurs as a white to yellowishwhite, hygroscopic, odorless powder.


DS 0.5-0.7

CARBOXYMETHYLCELLULOSE CALCIUM Basic Attributes

399.9568

399.207733

618-597-7

TSCA listed

3912310000

Characteristics

40.62000

5.22

1.2±0.1 g/cm3

557.1±50.0 °C at 760 mmHg

290.7±30.1 °C

1.623

Carboxymethylcellulose calcium is a stable, though hygroscopic material. It should be stored in a well-closed container in a cool, dry place.

Safety Information

NONH for all modes of transport

WGK 3

Carboxymethylcellulose calcium is a stable, though hygroscopic material. It should be stored in a well-closed container in a cool, dry place.

P261-P280-P284-P304 + P340-P342 + P311

H317-H334

CARBOXYMETHYLCELLULOSE CALCIUM Use and Manufacturing

Methods of Manufacturing

It is obtained by adding calcium hydroxide to the aqueous solution of sodium carboxymethyl cellulose and making it precipitate.

Uses

Thickener; binder; non-sticky dispersant; disintegrant. The maximum amount prescribed by Japan is 2% (total amount when used alone or in combination). It is used for soup powder molding. When it dissolves, it swells due to water to promote disintegration and dispersion. For cocoa powder, instant coffee, powdered soft drinks and other solid and powdered foods, it has the effect of promoting dispersion and dissolution in water. Adding 1% to 2% to chocolate biscuits is not easy to stick teeth and improve the taste. This product absorbs water and swells, and will not be digested and absorbed after taking people. It has a sense of fullness and can be used as a weight-adjusting food.


Pharmaceutic aid (tablet disintegrant).

Production

Cellulose, obtained from wood pulp or cotton fibers, is carboxymethylated, followed by conversion to the calcium salt. It is then graded on the basis of its degree of carboxymethylation and pulverized.

Drug Function and Efficacy

It can inhibit the excessive secretion of intestinal fluid. It promotes the absorption of intestinal fluid, reduces the amount of water in the intestine, and thus reduces the water content of the stool, which prevents diarrhea. It can inhibit intestinal peristalsis, thus preventing diarrhea caused by hypermotility of the intestine. It can effectively inhibit the Vero toxin produced by O157 Escherichia coli and the damage to intestinal mucosal epithelial cells caused by it.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • PATEL CHEM SPECIALITIES LTD

    United States United States
    Active
  • CBC Co., Ltd.

    China China
    Active
  • DKSH Performance Materials China Ltd.

    China China
    Active

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