3H-1,2-Benzodithiol-3-one-1,1-dioxide
-
3H-1,2-Benzodithiol-3-one-1,1-dioxide
structure -
-
CAS No:
66304-01-6
-
Formula:
C7H4O3S2
-
Chemical Name:
3H-1,2-Benzodithiol-3-one-1,1-dioxide
-
Synonyms:
3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE;3H-1,2-BENZODITHIOL-ONE 1,1-DIOXIDE;3H-1,2-BENZODITHIO-3-ONE-1,1-DIOXIDE;BEAUCAGE REAGENT;3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE, 9 9%;BSS;3H-1,2-BENZODITHIOLE-3-ONE-1,1-DIOXIDE(BSS);3H-1,2-BENZODITHIOL-3-ONE1,1-DIOXIDE(BSS)
- Categories:
-
CAS No:
3H-1,2-Benzodithiol-3-one-1,1-dioxide Basic Attributes
200.23
199.960190
4180332
-0
DTXSID10388381
29309090
Characteristics
84.9
1.1
1.7±0.1 g/cm3
103-107 °C(lit.)
414.6°C at 760 mmHg
204.6±24.0 °C
1.690
2-8°C
3H-1,2-Benzodithiol-3-one-1,1-dioxide Use and Manufacturing
Compound 301: (Sp)-CAGT-phosphorothioate (R = H): ( 'p)-CAGT-H- phosphonate-oxalyl linker-CPG was treated by 0.2 M Beaucage Reagent/CH3CN-BSA (9: 1 , v/v), stirred for 1 h at rt, then washed successively with CS2 and acetonitrile and dried under reduced pressure. The resultant CPG was treated with 2 mL of 28percent aqueous NH3 and stirred fori 8 h at rt. After removal of NH3 under reduced pressure, the resulting product was analyzed by LC/MS and HPLC.Example 23 (2R)-Bis(2-cyanoethyl)-2-octanoylamino-2-phenylethylthiophosphate To a solution of the compound prepared in Reference example 8 (1.16 g) in acetonitrile (11 ml) was added 3H-1, 2-benzodithiol-3-one 1, 1-dioxide (590 mg), the mixture was stirred for 1 hour at room temperature. The reaction mixture was concentrated. The residue was purified by column chromatography on silica gel (hexane:ethyl acetate=1:1) to give the compound (797 mg) of the present invention having the following physical data. TLC: Rf 0.24(Hexane:Ethyl acetate=1:1); NMR(CDCl3): delta7.50-7.22(m, 5H), 6.28(d, J=8.4 Hz, 1H), 5.40-5.30(m, 1H), 4.40-4.26(m, 2H), 4.26-4.00(m, 4H), 2.75-2.60(m, 4H), 2.26(t, J=7.5 Hz, 2H), 1.78-1.50(m, 2H), 1.50-1.18(m, 8H), 0.88(t, J=6.6 Hz, 3H).
Computed Properties
Molecular Weight:200.2
XLogP3:1.1
Hydrogen Bond Acceptor Count:4
Exact Mass:199.96018633
Monoisotopic Mass:199.96018633
Topological Polar Surface Area:84.9
Heavy Atom Count:12
Complexity:301
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 3H-1,2-Benzodithiol-3-one-1,1-dioxide
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![United States]()
US
6 YRS
Business licensedTrader Supplier of API & Nutraceuticals -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 66304-01-6Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
2-Bromophenacyl bromide, 90%
49851-55-0
-
1H-Indazol-7-ol
81382-46-9
-
6-Chloro-4-forMyl-nicotinic acid
1031433-06-3
-
3-Hydroxy-2,4,5-trifluorobenzoic acid Formula
116751-24-7
-
2-Methyl-1-heptene Formula
15870-10-7
-
1-(3,5-Dinitrophenyl)ethanone Formula
14401-75-3
-
α-Amino-3-bromobenzeneacetic acid Structure
79422-73-4
-
6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97% Structure
499770-85-3
-
What is Allyl methacrylate
96-05-9
-
What is ethyl 5-hydroxy-2-Methylnicotinate
60390-47-8
3H-1,2-Benzodithiol-3-one-1,1-dioxide
SDSRequest for Quotation