Isopropenylboronic acid pinacol ester
-
Isopropenylboronic acid pinacol ester
structure -
-
CAS No:
126726-62-3
-
Formula:
C9H17BO2
-
Chemical Name:
Isopropenylboronic acid pinacol ester
-
Synonyms:
2-Isopropenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;Isopropenylboronic acid pinacol ester;2-(1-Methylethenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Isopropenyl boronic acid pinacol ester;4,4,5,5-tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-(1-methylethenyl)-1,3,2-dioxaborolane;4,4,5,5-Tetramethyl-2-(isopropenyl)-1,3,2-dioxaborolane;2-Isopropenyl-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(Isopropenylboronic acid pinacol ester)
- Categories:
-
CAS No:
Description
Isopropenylboronic acid pinacol ester is a versatile ester reagent used for palladium-catalyzed Suzuki-Miyaura cross-coupling processes, inverse-electron-demand Diels-Alder reaction, Simmons-Smith cyclopropanation reaction, polyene cyclization, stereoselective aldol reactions, Grubbs cross-metathesis reaction, intramolecular Suzuki-Miyaura reaction, Stereoselective cross-metathesis, dipolar cycloaddition, iodosulfonylation, asymmetric conjugate addition and intramolecular hydroacylation and pre
Characteristics
18.5
Clear, colorless to brown Liquid
0.894
157-161 °C
47-49 °C (9 mbar)
42 °C
1.432
2-8°C
Safety Information
Ⅲ
IRRITANT
UN 1993
3
10-36/37/38-43
16-26-36/37
Xi
P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, P501
H226
|Warning|H226 (97.73%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 44 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Isopropenylboronic acid pinacol ester Use and Manufacturing
Dissolve isopropenyl bromide (89.58, 0.7411101) in 75011 ^ tetrahydrofuran, dropwise add bis (diisopropylAmine) boron chloride (183 g, 0.74 mol), lithium metal (10.4 g, 1.5 ml), and 110 mL of tetrahydrofuran were added dropwise a process controlThe reaction temperature was -10 ° C to 0 ° C. After completion of the dropwise addition, the temperature was maintained for 1 hour, The reaction was then continued for 5 hours at 25 ° C.After the completion of the reaction, pinacol (988, 0.83111 01), 2, 6-di-tert-butyl-4-methylphenol (4.58) and 1201 tetrahydrofuran were added and the temperature was raised to reflux.Distillation under reduced pressure afforded the colorless transparent liquid isopropenylboronic acid pinacol ester 82.lg, yield 66percent, GC: 99.7percent2, 6-di-tert-butyl-4-methylphenol (0.45 g) was added for long-term storage.
suzuki reaction
Computed Properties
Molecular Weight:168.04
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:168.1321599
Monoisotopic Mass:168.1321599
Topological Polar Surface Area:18.5
Heavy Atom Count:12
Complexity:193
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Isopropenylboronic acid pinacol ester
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
6 YRS
Business licensed Certified factoryManufactory Supplier of Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine,Medetomidine Hydrochloride,Selank,5-Amino-1MQ,Thymosin Alpha 1,TB500,SS-31,MOTS-c,GLOW,KLOW,KPV,VIP,Inulin,Pinealon,Adamax,Humanin,L-serine,Sh-oligopeptide-7,Mushroom Chitosan,Sodium C14-16 olefin sulfonate,Disodium Lauryl Sulfosuccinate,Phenothiazine,Piroctone Olamine,Saffron extract,Citrus Pectin,Apple Pectin,Alpha-Bisabolol,Climbazole,Octocrylene,Avobenzone,Diethylamino hydroxybenzoyl hexyl benzoate,Bemotrizinol,Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine,Orotic Acid Anhydrous,Rice Peptide,Salidroside,Sulforaphane,Soy Isoflavones,Alginate Oligosaccharide,Acetoacetoxyethyl methacrylate,Menthyl Isovalerate,Refined fish oil,krill oil,Cooling agent WS12,Cooling agent WS23,Cooling agent WS3,Cooling agent WS5,Cooling agent WS10,Cooling Agent WS27,Menthyl Lactate,Menthyl PCA,Ethyl ascorbic acid,Ectoin,Milk thistle extract,NAD+,GHK-Cu,Glutathione,HCG,Soy Lecithin,Mung bean peptide,Sea cucumber peptide,Lactose anhydrous,Lactose monohydrate,Vegan Vitamin D3,Riboflavin Sodium Phosphate,DSIP,AHK-CuInquiryCAS No.: 126726-62-3Grade: Chemical GradeContent: 99%
Learn More Other Chemicals
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
CYCLOPENTYL-CARBAMIC ACID PHENYL ESTER
58713-31-8
-
2'-Deoxy-N-trimethylsilyl-3'-O-trimethylsilylcytidine 5'-phosphoric acid bis(trimethylsilyl) ester
32645-72-0
-
4,6-Dichloro-1H-indole-2,3-dicarboxylic acid diethyl ester Formula
146012-24-0
-
2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester Formula
1154228-17-7
-
Dibenzoic acid 2-ethylhexamethylene ester Formula
25724-54-3
-
1,4-DIBENZYL-7-PHENYL-6-THIOXO-1,4,7-TRIAZA-SPIRO[4.4]NON-8-ENE-9-CARBOXYLIC ACID ETHYL ESTER Structure
885722-38-3
-
4,5-Dichloro-8-methylquinoline-3-carboxylic acid ethyl ester Structure
1019462-72-6
-
What is 3-(2,6-DICHLORO-PHENYL)-5-ISOPROPYL-ISOXAZOLE-4-CARBOXYLIC ACID METHYL ESTER
278597-28-7
-
What is 3-(β-D-Glucopyranosyloxy)-2-hydroxybenzoic acid 3-(1,3-dihydro-3-oxoisobenzofuran-1-yl)propyl ester
94617-34-2
Isopropenylboronic acid pinacol ester
SDSRequest for Quotation