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Hydroxydiethylphenamine

Hydroxydiethylphenamine structure

CAS No:
13073-96-6
Formula:
C21H28N2O2.2ClH
Chemical Name:
Hydroxydiethylphenamine
Synonyms:
2-(2-(4-(Diphenylmethyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride;Ethanol, 2-(2-(4-(diphenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride;Hydroxydiethylphenamine;Decloxizine Dihydrochloride;1-[2-(2-Hydroxyethoxy)ethyl]-4-α-phenylbenzyldiethylenediaMine Dihydrochloride;2-[2-[4-(DiphenylMethyl)-1-piperazinyl]ethoxy]ethanol Hydrochloride;Autokar;Rescupal
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

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Description

Decloxizine dihydrochloride(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.

Hydroxydiethylphenamine Basic Attributes

Molecular Weight：

413.386

Exact Mass：

412.16800

EC Number：

1312995-182-4

DSSTox ID：

DTXSID20156699

Characteristics

PSA：

35.9

XLogP3：

3.88230

Density：

1.115g/cm3

Boiling Point：

472.4ºC at 760mmHg

Flash Point：

239.5ºC

Vapor Pressure：

9.93E-10mmHg at 25°C

Hydroxydiethylphenamine Use and Manufacturing

Hydroxyzine (H996500) impurity.

Computed Properties

Molecular Weight:413.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:412.1684336
Monoisotopic Mass:412.1684336
Topological Polar Surface Area:35.9
Heavy Atom Count:27
Complexity:328
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It has antihistamine effect, and has antiasthmatic and sedative effects.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound chlorprenaline and bromhexine tablets
Ingredients	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Indication	1. It has an additive effect when used in combination with other bronchial β2 receptor agonists. 2. When this product is used in combination with other β2 receptor agonists, the efficacy is reduced and adverse reactions such as hand tremors and palpitations may be more obvious. 3. If used in combination with phosphodiesterase inhibitors such as theophylline or anticholinergic antiasthmatic drugs, its bronchial dilation and asthma relief effects are enhanced. 4. Bromhexine hydrochloride can increase the concentration of tetracycline antibiotics in the bronchi.
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
Manufacturer	Zhejiang Dongri Pharmaceutical Co., Ltd.

Compound chlorprenaline and bromhexine capsules
Ingredients	This product is a compound preparation, each tablet containing 5 mg of chlorprenaline hydrochloride, 10 mg of bromhexine hydrochloride, and 25 mg of deschlorohydroxyzine hydrochloride.
Indication	1. It has an additive effect when used in combination with other bronchial β2 receptor agonists. 2. When this product is used in combination with other bronchial β2 receptor agonists, the efficacy is reduced and adverse reactions such as hand tremors and palpitations may be more obvious. 3. If combined with phosphodiesterase inhibitors such as theophylline or anticholinergic antiasthmatic drugs, its effect of dilating the bronchi and relieving asthma is enhanced. 4. Bromhexine hydrochloride can increase the concentration of tetracycline antibiotics in the bronchi.
Specifications	Each tablet contains 5mg of chlorprenaline hydrochloride, 10mg of bromhexine hydrochloride, and 25mg of deschlorohydroxyzine hydrochloride
Manufacturer	Wanbangde Pharmaceutical Group Co., Ltd.

Deschlorohydroxyzine hydrochloride
Manufacturer	Taicang Pharmaceutical FACTORY

See More Related Drugs

Registered Holders

Wanbangde Pharmaceutical Group Co., Ltd.

China
Active
Taicang Pharmaceutical FACTORY

China
Active

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CAS No.: 13073-96-6

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Content: 98%

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White Powder Hydroxydiethylphenamine 13073-96-6

CAS No.: 13073-96-6

Grade: Pharmaceutical Grade

Content: 99%

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