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Thenalidine

Thenalidine structure

CAS No:
86-12-4
Formula:
C17H22N2S
Chemical Name:
Thenalidine
Synonyms:
4-Piperidinamine,1-methyl-N-phenyl-N-(2-thienylmethyl)-;Piperidine,1-methyl-4-(N-2-thenylanilino)-;Piperidine,1-methyl-4-N-thenylanilino-;2-Thenylamine,N-(1-methyl-4-piperidyl)-N-phenyl-;1-Methyl-N-phenyl-N-(2-thienylmethyl)-4-piperidinamine;1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine;1-Methyl-4-N-2-thenylanilinopiperidine;Thenophenopiperidine;Thenalidine;Sanbosten;Thenalidin;Thenaldine;Sandostene;1-Methyl-N-phenyl-N-(thiophen-2-ylmethyl)piperidin-4-amine;26548-71-0;943790-73-6
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

Description

Thenalidine is a dialkylarylamine and a tertiary amino compound.|Withdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.

Thenalidine Basic Attributes

Molecular Weight：

126.17954

Exact Mass：

286.43

EC Number：

201-651-5

UNII：

6U94N2D00F

DSSTox ID：

DTXSID1048835

ATC Code：

D - Dermatologicals|R - Respiratory system

HScode：

2934999090

Characteristics

PSA：

34.7

XLogP3：

3.78680

Density：

1.14g/cm3

Melting Point：

96 °C

Boiling Point：

159 °C

Flash Point：

204.1ºC

Refractive Index：

1.619

Drug Information

MeSH Entry Terms：

1-methyl-4-(N-2-thenylanilino)piperidine

Computed Properties

Molecular Weight:286.4
XLogP3:3.8
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:286.15036988
Monoisotopic Mass:286.15036988
Topological Polar Surface Area:34.7
Heavy Atom Count:20
Complexity:283
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes