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Olopatadine

Olopatadine structure

CAS No:
113806-05-6
Formula:
C21H23NO3
Chemical Name:
Olopatadine
Synonyms:
Dibenz[b,e]oxepin-2-acetic acid,11-[3-(dimethylamino)propylidene]-6,11-dihydro-,(11Z)-;Dibenz[b,e]oxepin-2-acetic acid,11-[3-(dimethylamino)propylidene]-6,11-dihydro-,(Z)-;(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid;11-[(Z)-3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid;Olopatadine;186084-05-9
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

Description

Olopatadine belongs to a kind of antihistamine reagent. It is a relatively selective H1-receptor antagonist and can inhibit the histamine release process from the mast cell, subsequently leading to temporary relief on the negative symptoms associated with histamine. It is devoid of effects on alpha-adrenergic, dopamine and muscarinic type I and II receptors. Its 0.1% solution can be used for topical administration to the eyes. It is indicated for the treatment of itching associated with allergi

Olopatadine Basic Attributes

Molecular Weight：

337.41

Exact Mass：

337.41

EC Number：

604-185-4

Characteristics

PSA：

49.8

XLogP3：

3.4

Density：

1.2±0.1 g/cm3

Melting Point：

188-189.5°

Boiling Point：

523.0±50.0 °C at 760 mmHg

Flash Point：

270.1±30.1 °C

Refractive Index：

1.641

Water Solubility：

H2O: soluble

Safety Information

Precautionary statement(s)：

P264, P270, P273, P301+P310, P301+P312, P321, P330, P391, P405, P501

Hazard Statements：

H301

Olopatadine Use and Manufacturing

Anti-allergic. Allergic rhinitis, allergic conjunctivitis, urticaria, skin diseases accompanied by itching symptoms (eczema, erythema multiforme, etc.) and asthma.

Drug Function and Efficacy

H1 receptor antagonist, used for treating allergic conditions such as allergic rhinitis and conjunctivitis by inhibiting histamine-mediated allergic reactions

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

EQUATE OLOPATADINE HYDROCHLORIDE- olopatadine hydrochloride_solution
Manufacturer	WAL-MART STORES, INC.,

OLOPATADINE HYDROCHLORIDE OPHTHALMIC SOLUTION- olopatadine hydrochloride ophthalmic solution_solution
Manufacturer	TARGET CORPORATION

LEADER OLOPATADINE HYDROCHLORIDE- olopatadine hydrochloride_solution
Manufacturer	CARDINAL HEALTH

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Registered Holders

KYOWA KIRIN CO LTD

United States
Inactive

Recommended Suppliers of Olopatadine

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

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Olopatadine

CAS No.: 113806-05-6

Content: 99.00%

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