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Saracatinib

Saracatinib structure

CAS No:
379231-04-6
Formula:
C27H32ClN5O5
Chemical Name:
Saracatinib
Synonyms:
4-Quinazolinamine,N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-;N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine;4-(6-Chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxyquinazoline;7-[2-[4-Methylpiperazin-1-yl]ethoxy]-5-[[tetrahydropyran-4-yl]oxy]-4-[[6-chloro-2,3-methylenedioxyphenyl]amino]quinazoline;AZD 0530;Saracatinib;AZD0530;AZD 530;AZD-0530
Categories:
Active Pharmaceutical Ingredients > Antineoplastic Agents

Description

Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk and shows high selectivity over other tyrosine kinases.

Saracatinib Basic Attributes

Molecular Weight：

542.03

Exact Mass：

542.03

EC Number：

1592732-453-0

Characteristics

PSA：

90.4

XLogP3：

4.1

Density：

1.3±0.1 g/cm3

Boiling Point：

671.25°C at 760 mmHg

Flash Point：

359.8±31.5 °C

Refractive Index：

1.641

Saracatinib Use and Manufacturing

An oral, selective dual inhibitor of Src and ABL kinase.

Recommended Suppliers of Saracatinib

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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Saracatinib 98% Powder Zhishang

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Creative Enzymes Contact Supplier

US
6 YRS

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Saracatinib(AZD0530)

CAS No.: 379231-04-6

Content: 99%

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