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Lomerizine

Lomerizine structure

CAS No:
101477-55-8
Formula:
C27H30F2N2O3
Chemical Name:
Lomerizine
Synonyms:
Piperazine,1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-;1-[Bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;Lomerizine
Categories:
Active Pharmaceutical Ingredients > Antipyretic Analgesics

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Description

1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine is a diarylmethane.|Used to treat migraines.

Lomerizine Basic Attributes

Molecular Weight：

468.54

Exact Mass：

468.54

UNII：

DEE37CY4VO

DSSTox ID：

DTXSID6048387

Characteristics

PSA：

34.2

XLogP3：

4.77360

Density：

1.203±0.06 g/cm3(Predicted)

Melting Point：

213-215ºC

Boiling Point：

527.3±45.0 °C(Predicted)

Flash Point：

272.7ºC

Vapor Pressure：

3.31E-11mmHg at 25°C

Drug Information

MeSH：

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

MeSH Entry Terms：

1-(bis(4-fluorophenyl)methyl)-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride

Lomerizine Use and Manufacturing

antimigraine, cerebral vasodilator, Ca channel blocker

Computed Properties

Molecular Weight:468.5
XLogP3:4.9
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:468.22244915
Monoisotopic Mass:468.22244915
Topological Polar Surface Area:34.2
Heavy Atom Count:34
Complexity:568
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Lomerizine

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

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High Quality 99% Purity of Lomerizine CAS NO 101477-55-8 ISO 9001:2005 REACH Verified Producer

CAS No.: 101477-55-8

Grade: Industrial Grade

Content: 99%

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