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Home > Encyclopedia > 4-CHLORO-3-HYDROXYPYRIDINE

4-CHLORO-3-HYDROXYPYRIDINE

4-CHLORO-3-HYDROXYPYRIDINE structure

4-CHLORO-3-HYDROXYPYRIDINE 

structure
  • CAS No:

    96630-88-5

  • Formula:

    C5H4ClNO

  • Chemical Name:

    4-CHLORO-3-HYDROXYPYRIDINE

  • Synonyms:

    4-CHLORO-3-HYDROXYPYRIDINE;4-CHLORO-3-PYRIDINOL;3-Pyridinol,4-chloro-(9CI);4-CHLORO-3-HYDROXYPYRIDINE 97%;4-Chloropyridin-3-ol

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

4-CHLORO-3-HYDROXYPYRIDINE Basic Attributes

129.54

128.998138

-0

DTXSID70376204

2933399090

Characteristics

33.1

1.1

1.4±0.1 g/cm3

298.2°C at 760 mmHg

134.1±21.8 °C

1.584

Safety Information

IRRITANT

NONH for all modes of transport

3

22-41

26

Xn

P280-P305 + P351 + P338

H302-H318

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

4-CHLORO-3-HYDROXYPYRIDINE Use and Manufacturing

a) A solution of diazenedicarboxylic acid diethyl ester (0.1572 mol) in THF (163 ml) was added dropwise to a mixture of Example 66 Preparation of (4bR, 8aR, 9R)-N-(3-(2-(2-methoxyethoxy)ethoxy)pyridin-4-yl)-ll- methyl-6, 7, 8, 8a, 9, 10-hexahydro-5H-9, 4b-(epiminoethano)phenanthren-3-amine (66), hydrochloride salt Step 1. Synthesis of 4-chloro-3-(2-(2-methoxyethoxy)ethoxy)pyridine, A mixture of Step A: Preparation of 4-Chloro-3-methoxypyridine. To a cold solution of

Computed Properties

Molecular Weight:129.54
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:128.9981414
Monoisotopic Mass:128.9981414
Topological Polar Surface Area:33.1
Heavy Atom Count:8
Complexity:78.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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