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2-Hydroxy-3-trifluoromethylpyridine

2-Hydroxy-3-trifluoromethylpyridine structure

CAS No:
22245-83-6
Formula:
C6H4F3NO
Chemical Name:
2-Hydroxy-3-trifluoromethylpyridine
Synonyms:
2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE;3-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDIN-2-ONE;3-(TRIFLUOROMETHYL)-2-PYRIDONE;BUTTPARK 24\01-66;3-(Trifluoromethyl)pyridin-2-one;3-Trifluoromethyl-pyridin-2-ol;2-Hydroxy-3-(trifluoromethyl)pyridine 97%;2-Hydroxy-3-(trifluoromethyl)pyridine97%
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

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Description

White powder

2-Hydroxy-3-trifluoromethylpyridine Basic Attributes

Molecular Weight：

163.1

Exact Mass：

163.024506

EC Number：

1308068-626-2

DSSTox ID：

DTXSID80394934

HScode：

2933399090

Characteristics

PSA：

29.1

XLogP3：

1.1

Density：

1.4±0.1 g/cm3

Melting Point：

150-153°C

Boiling Point：

223.7°C at 760 mmHg

Flash Point：

107.7±25.9 °C

Refractive Index：

1.457

Vapor Pressure：

0.0947mmHg at 25°C

Safety Information

Hazard category：

IRRITANT

hazard class code：

36/37/38-65-20/21/22-20/21-36-25

safety instructions：

26-36/37/39-36-45

Marks：

Xi,Xn,T

Hazard note：

Irritant

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H228 (50%): Flammable solid [Danger Flammable solids]|P210, P240, P241, P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P405, and P501|Aggregated GHS information provided by 4 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Hydroxy-3-trifluoromethylpyridine Use and Manufacturing

Methods of Manufacturing

0.19 g (2.0 mmol) of 2-hydroxypyridine and 0.11 g (0.6 mmol) of ferrocene were weighed and placed in a two-neck flask and the atmosphere in the flask was replaced with argon. The following materials were added thereinto: 8.0 ml of dimethyl sulfoxide, 2.0 ml of a 3.0 mol/l dimethyl sulfoxide solution of trifluoromethyl iodide and 0.4 ml of a 30percent hydrogen peroxide aqueous solution, and the mixture was stirred for 20 minutes. During the stirring, the temperature of the reaction system rose up in the range of from 40°C to 50°C. Thereafter, the resulting solution was cooled to room temperature. Formation of 2-hydroxy-3-trifluoromethylpyridine (

Use Classification：

Environmental transformation -> Pesticide transformation products (metabolite, successor)

Agrochemical：

HTF (SSRE-021) is a known environmental transformation product of Flazasulfuron.

Computed Properties

Molecular Weight:163.10
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Exact Mass:163.02449824
Monoisotopic Mass:163.02449824
Topological Polar Surface Area:29.1
Heavy Atom Count:11
Complexity:239
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 22245-83-6

Content: 99.00%

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CAS No.: 22245-83-6

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chemtour Contact Supplier

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CAS No.: 22245-83-6

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Content: 99%

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Content: 99%

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Guide of 2-Hydroxy-3-trifluoromethylpyridine

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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2-Hydroxy-3-trifluoromethylpyridine

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