2-Hydroxy-6-methyl-5-nitropyridine
-
2-Hydroxy-6-methyl-5-nitropyridine
structure -
-
CAS No:
28489-45-4
-
Formula:
C6H6N2O3
-
Chemical Name:
2-Hydroxy-6-methyl-5-nitropyridine
-
Synonyms:
2-HYDROXY-5-NITRO-6-PICOLINE;2-HYDROXY-6-METHYL-5-NITROPYRIDINE;6-METHYL-5-NITRO-2-PYRIDINOL;6-HYDROXY-3-NITRO-2-PICOLINE;6-HYDROXY-2-METHYL-3-NITROPYRIDINE;2-Hydorxy-5-Nitro-6-Picoline;6-METHYL-5-NITROPYRIDIN-2-OL;and6-HYDROXY-3-NITRO-2-PICOLINE
- Categories:
-
CAS No:
Characteristics
74.9
0.1
Light brown to brown Crystalline Powder
1.4±0.1 g/cm3
230-232 °C
390.8°C at 760 mmHg
190.2±27.9 °C
1.605
Safety Information
36/37/38-22
37/39-26
Xi,Xn
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 162 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Hydroxy-6-methyl-5-nitropyridine Use and Manufacturing
(b) 6-Amino-3-nitro-2-picoline (20 g, 0.131 mol) was suspended in a mixture of conc. H2S04 (23.7 ml) and water (335 ml). More cone. H2S04 (20 ml) was added under ice- cooling, but the amine did not dissolve completely. The suspension was added in ice (100 g) before a solution of NaNO2 (13.53 g, 0.196 mol) in water (40 ml) was added drop wise. Gas evolution was observed. The brown suspension was stirred at 10°C for 1 hr, filtered and washed with water. The brown product was dried (freeze dryer) to achieve 15.78 g (78 percent) of 6-hydroxy-3-nitro-2-picoline.The raw material 2 (5g) was added to 15mL water, the external temperature -5 dropping concentrated sulfuric acid 25mL, keep the internal temperature 0 ~ -5 under the conditions of slowly dropping NaNO6-hydroxy-3-nitro-2-picoline 6-hydroxy-3-nitro-2-picoline The product derived from step 1 (0.796g, 4.7mmol) was added to a of solution HBr (33percent) in acetic acid (5ml), the mixture was stirred at 60°C for 2h and concentrated under reduced pressure.
Computed Properties
Molecular Weight:154.12
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:154.03784206
Monoisotopic Mass:154.03784206
Topological Polar Surface Area:74.9
Heavy Atom Count:11
Complexity:272
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-Hydroxy-6-methyl-5-nitropyridine
-
![China]()
CN
4 YRS
Business licensedTrader Supplier of Fluorine containing fine chemicals PharmaceuticalInquiryCAS No.: 28489-45-4Content: 99% -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides,Organic Intermediates,OLED IntermediatesInquiryCAS No.: 28489-45-4Grade: Pharmaceutical GradeContent: 99%
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8
2-Hydroxy-6-methyl-5-nitropyridine
SDSRequest for Quotation