Flucarbazone-sodium

418.279

418.017090

605-921-7

76VQM4L12C

DTXSID3034614

Colorless, crystalline powder|Solid, crystalline, white

115

-0.89(pH4);-1.85(pH7)

1.59

200 deg C (decomposes)

463.7ºC at 760mmHg

234.2ºC

Solubilities in organic solvents (g/l at 20 °C) Dimethylsulfoxide: 250 Poly(ethylene glycol): 48 Acetonitrile: 6.4 2‐Propanol: 0.27 Xylene: <0.1;In water, 44 g/L at 20 deg C (pH 9)

Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water. /Residential users/

<1X10-9 Pa at 20 deg C

LD50 in rats (mg/kg): >5000 orally; >5000 dermally; LD50 by inhalation in rats: >5.13 mg/l; LC50 in bluegill sunfish, rainbow trout: >99.3, >96.7 mg/l

Odorless

pKa = 1.9|pKa = 1.9 /Flucarbazone/

52/53

61

XZ4205000

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.|Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. /Everest 70% Water Dispersible Granular Herbicide/|CONTAINER DISPOSAL: Non-refillable container. Do not reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Offer for recycling, if available or puncture and dispose of in a sanitary landfill, or by incineration,or, if allowed by state and local authorities, by burning. If burned, stay out of smoke. /Everest 70% Water Dispersible Granular Herbicide/|Safe Disposal of Pesticides. The best way to dispose of small amounts of excess pesticides is to use them - apply them - according to the directions on the label. If you cannot use them, ask your neighbors whether they have a similar pest control problem and can use them. If all of the remaining pesticide cannot be properly used, check with your local solid waste management authority, environmental agency, or health department to find out whether your community has a household hazardous waste collection program or a similar program for getting rid of unwanted, leftover pesticides. These authorities can also inform you of any local requirements for pesticide waste disposal. /Residential users/|Safe Disposal of Pesticides. An empty pesticide container can be as hazardous as a full one because of residues left inside. Never reuse such a container. When empty, a pesticide container should be rinsed carefully three times and the rinsewater thoroughly drained back onto the sprayer or the container previously used to mix the pesticide. Use the rinsewater as a pesticide, following label directions. Replace the cap or closure securely. Dispose of the container according to label instructions. Do not puncture or burn a pressurized container like an aerosol - it could explode. Do cut or puncture other empty pesticide containers made of metal or plastic to prevent someone from reusing them. Wrap the empty container and put it in the trash after you have rinsed it. /Residential users/

Applicators and other handlers must wear: Long-sleeved shirt and long pants. Chemical resistant gloves (Category A) made of materials such as butyl rubber greater than or equal to 14 mils, natural rubber greater than or equal to 14 mils, neoprene rubber greater than or equal to 14 mils, or nitrile rubber greater than or equal to 14 mils. Shoes plus socks. /Everest 70% Water Dispersible Granular Herbicide/|... Restricted-entry interval (REI) of 12 hours following application. Exception: If the product is soil-injected or soil-incorporated, the Worker Protection Standard, under certain circumstances, allows workers to enter the treated area if there will be no contact with anything that has been treated. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water, is: coveralls, chemical resistant gloves (Category A) made of materials such as butyl rubber greater than or equal to 14 mils, natural rubber greater than or equal to 14 mils, neoprene rubber greater than or equal to 14 mils, or nitrile rubber greater than or equal to 14 mils, shoes plus socks. /Everest 70% Water Dispersible Granular Herbicide/|When handlers use closed systems, enclosed cabs or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS. /Everest 70% Water Dispersible Granular Herbicide/

Extinguishing Media: Water, CO2, dry chemical, foam. /Everest 70 WDG/|Keep out of smoke, cool exposed containers with water spray. Fight ire from upwind position. Use SCBA /self-contained breathing apparatus/. Contain run-off to prevent entry into sewers or waterways. Equipment used in fires may become contaminated. /Everest 70 WDG/

Do not contaminate water when disposing of equipment washwaters. /Everest 70% Water Dispersible Granular Herbicide/|Isolate area and keep unauthorized people away. Do not walk through spilled material. Avoid breathing dusts and skin contact. Avoid generating dust (a fine water spray mist, plastic film cover, or floor sweeping compound may be used if necessary). Use recommended protective equipment while carefully sweeping up spilled material. Place in covered container for reuse or disposal. Scrub contaminated area with soap and water. Rinse with water. Use dry absorbent material such as clay granules to absorb and collect wash solution for proper disposal. Contaminated soil may have to be removed and disposed. Do not allow material to enter streams, sewers, or other waterways. /Everest 70 WDG/|If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label./Residential users/|After Applying a Pesticide, Indoors or Outdoors. To remove pesticide residues, use a bucket to rinse tools or equipment three times, including any containers or utensils that you used when mixing the pesticide. Then pour the rinsewater into the pesticide sprayer and reuse the solution by applying it according to the pesticide product label directions. After applying any pesticide wash your hands and any other parts of your body that may have come in contact with the pesticide. To prevent tracking pesticides inside, remove or rinse your boots or shoes before entering your home. Wash any clothes that have been exposed to a lot of pesticide separately from your regular wash. /Residential users/

Use this product only in accordance with its labeling and with Worker Protection Standard, 40 CFR part 170. /Everest 70% Water Dispersible Granular Herbicide/|Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. /Everest 70% Water Dispersible Granular Herbicide/|Users should: Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Remove clothing immediately if pesticide gets inside. Then wash thoroughly and put on clean clothing. Remove PPE /Personal Protective Equipment/ immediately after handling this product. Wash the outside of gloves before removing. As soon as possible, wash thoroughly and change into clean clothing. /Everest 70% Water Dispersible Granular Herbicide/|Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.. /Everest 70% Water Dispersible Granular Herbicide/|For more Preventive Measures (Complete) data for Flucarbazone-sodium (17 total), please visit the HSDB record page.

LC50 Rat inhalation >5.13 mg/L /Duration not specified/|LD50 Rat dermal >5000 mg/kg|LD50 Rat oral >5000 mg/kg|LD50 Rat male oral > 5000 mg/kg /Everest technical/|For more Non-Human Toxicity Values (Complete) data for Flucarbazone-sodium (13 total), please visit the HSDB record page.

Flucarbazone-sodium's production may result in its release to the environment through various waste streams; its use as a herbicide(1) will result in its direct release to the environment(SRC).

TERRESTRIAL FATE: Flucarbazone-sodium will dissociate in the environment to form flucarbazone; therefore the following estimated physical information will be based on the acid form of flucarbazone(SRC). Based on a classification scheme(1), an estimated Koc value of 36(SRC), determined from a structure estimation method(2), indicates that flucarbazone is expected to have very high mobility in soil(SRC). The pKa of flucarbazone is 1.9(3), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Volatilization from moist soil is not expected because the compound exists as an anion and anions do not volatilize(SRC). Flucarbazone is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.5X10-11 mm Hg at 25 °C(SRC), determined from a fragment constant method(5). The aerobic biodegradation half-life of flucarbazone-sodium in soil is 64 to 76 days(6), indicating that biodegradation is not an important environmental fate process in soil(SRC).|AQUATIC FATE: Flucarbazone-sodium will dissociate in the environment to form flucarbazone; therefore the following estimated physical information will be based on the acid form of flucarbazone(SRC). Based on a classification scheme(1), an estimated Koc value of 36(SRC), determined from a structure estimation method(2), indicates that flucarbazone is not expected to adsorb to suspended solids and sediment(SRC). A pKa of 1.9(3) indicates flucarbazone will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(SRC). Flucarbazone-sodium is stable to hydrolysis at pH 4, 7 and 9(4). According to a classification scheme(5), an estimated BCF of 3(SRC), from its log Kow of -1.84(3) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). The anaerobic biodegradation half-life of flucarbazone-sodium in water is 66 to 104 days(4), indicating that biodegradation is not an important environmental fate process in water(SRC).|ATMOSPHERIC FATE: Flucarbazone-sodium will dissociate in the environment to form flucarbazone; therefore the following estimated physical information will be based on the acid form of flucarbazone(SRC). According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), flucarbazone, which has an estimated vapor pressure of 2.5X10-11 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase flucarbazone-sodium may be removed from the air by wet or dry deposition(SRC).

Flucarbazone-sodium is stable to hydrolysis at pH 4, 7 and 9(1). Flucarbazone-sodium is also stable to photodegradation in water and soil(1).

Flucarbazone-sodium will dissociate in the environment to form the acid form of flucarbazone(SRC). An estimated BCF of 3 was calculated in fish for flucarbazone(SRC), using a log Kow of -1.84(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Flucarbazone-sodium will dissociate in the environment to form the acid form of flucarbazone(SRC). Using a structure estimation method based on molecular connectivity indices(1), the Koc of flucarbazone can be estimated to be 36(SRC). According to a classification scheme(2), this estimated Koc value suggests that flucarbazone is expected to have very high mobility in soil.

Flucarbazone-sodium will dissociate in the environment to form the acid form of flucarbazone(SRC). A pKa of 1.9(1) indicates flucarbazone will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(SRC).

Occupational exposure to flucarbazone-sodium may occur through inhalation of dust and dermal contact with this compound at workplaces where flucarbazone-sodium is produced or used. Use data indicate that the general population may be exposed to flucarbazone-sodium via dermal contact with fields treated with flucarbazone-sodium. (SRC)

There were no sex-related differences in the absorption, distribution, metabolism or excretion. Based on urinary excretion, absorption was 15-30% and maximum plasma concentrations were achieved within 30 minutes. At sacrifice, tissues and carcass contained less than 1% of radioactivity. The highest residue in the tissues was in the liver. Greater than 90% of the administered dose was eliminated within 24 hours. The major component in urine and feces was unchanged parent which represented 90-95% of the administered dose. /From table/

Metabolized via two pathways. One pathway involved the oxidative decarboxylation of sulfonamide lactate to form sulfonamide acetate. The other pathway involved the hydrolysis of sulfonamide lactate and sulfonamide acetate to give sulfonamide. /From table/

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/

MKH 6562

Water dispersible granule|95.6% technical product|PREMIX PARTNERS: Chlorsulfuron|Dupont Finesse Grass & Broadleaf Herbicide (E. I. Du Pont De Nemours and Co., Inc., S300/419 46.7% Flucarbazone-sodium, 25% Chlorsulfuron|For more Formulations/Preparations (Complete) data for Flucarbazone-sodium (11 total), please visit the HSDB record page.

The WHO Recommended Classification of Pesticides by Hazard identifies flucarbazone-sodium as unlikely to present an acute hazard in normal use; Main Use: herbicide.

Determination of residues in soil or water by lc/ms/ms

Agrochemicals -> Herbicides