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(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate

(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate structure

CAS No:
50298-96-9
Formula:
C18H23NO4
Chemical Name:
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate
Synonyms:
Benzeneacetic acid,α-(acetyloxy)-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;Benzeneacetic acid,α-(acetyloxy)-,8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,endo-(±)-;Benzeneacetic acid,α-(acetyloxy)-,8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,endo-;(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate;Acetylhomatropine

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(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate Basic Attributes

Molecular Weight：

317.37952

Exact Mass：

317.38

Characteristics

PSA：

66.8

(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate Use and Manufacturing

Methods of Manufacturing

The mandelic acid and acetyl chloride are heated to reflux to generate acetyl mandelic acid, which is then chlorinated with thionyl chloride to obtain acetyl mandelic acid chloride. The latter is esterified with anhydrous tropineol under alkaline conditions to obtain the product .

Uses

Intermediate of post-matropine hydrobromide.

Material

Thionyl chloride

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Guide of (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate

Basic Attributes
Characteristics
Use and Manufacturing
Material
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(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α-(acetyloxy)benzeneacetate

SDS

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