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Home > Encyclopedia > 2-Amino-5-bromo-4-methylpyridine

2-Amino-5-bromo-4-methylpyridine

2-Amino-5-bromo-4-methylpyridine structure

2-Amino-5-bromo-4-methylpyridine 

structure
  • CAS No:

    98198-48-2

  • Formula:

    C6H7BrN2

  • Chemical Name:

    2-Amino-5-bromo-4-methylpyridine

  • Synonyms:

    5-BROMO-4-METHYL-PYRIDIN-2-YLAMINE;5-BROMO-4-METHYL-2-PYRIDINYLAMINE;2-AMINO-5-BROMO-GAMMA-PICOLINE;2-AMINO-5-BROMO-4-METHYLPYRIDINE;2-AMINO-5-BROMO-4-PICOLINE;2-AMINO-4-METHYL-5-BROMOPYRIDINE;2-Amino-5-bromo-4-methylpyridine 98%;2-AMINO-5-BROMO-4-PICOLINE (2-AMINO-5-BROMO-4-METHYLPYRIDINE)

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

Light yellow Cryst

2-Amino-5-bromo-4-methylpyridine Basic Attributes

187.04

185.979248

-0

DTXSID30355838

29333999

Characteristics

38.9

1.6

Cream Powder

1.6±0.1 g/cm3

148-151 °C(lit.)

254.2ºC at 760 mmHg

107.5±25.9 °C

1.617

soluble in methanol.

Safety Information

IRRITANT

NONH for all modes of transport

3

36/37/38

26-36-37/39-37

Xi

Irritant

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 45 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Amino-5-bromo-4-methylpyridine Use and Manufacturing

General procedure: To a mixture of 2-aminopyridine (0.5 mmol, 1 equiv), p-TSA (0.4 mmol, 0.8 equiv), 1-butylpyridinium bromide (1.5 mmol, 3 equiv) in a 50 mL Schlenk tube were added 1, 2-dimethoxyethane (2 mL) under air. Then HEXAMPLE 41 STR43 2-Amino-5-bromo-4-methylpyridine

Computed Properties

Molecular Weight:187.04
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:185.97926
Monoisotopic Mass:185.97926
Topological Polar Surface Area:38.9
Heavy Atom Count:9
Complexity:97.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

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