BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
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![BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/8c97d8125b5843409b068d0f93531b7f.png "BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-")
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
structure -
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CAS No:
300586-90-7
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Formula:
C14H11N3O
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Chemical Name:
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
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Synonyms:
iPSC Induction Enhancer II, OAC1;BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-;BAS 00287861;OAC1;N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide;N-(1H-pyrrolo[3,2-d]pyridin-5-yl)benzamide
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CAS No:
Description
OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.IC50 value: Target: Oct4 activatorin vitro: OAC1 enhances the formation of Oct4-GFP+ colonies and accelerates the dynamics of reprogramming. OAC1 enhanced reprogramming efficiency through a mechanism that is independent of endogenous Oct4 promoter demethylation. OAC1 enhanced reprogramming efficiency through a mechanism that is
Characteristics
57.8
2.1
white to beige
1.4±0.1 g/cm3
187.6±22.3 °C
1.755
DMSO: soluble 20mg/mL, clear
2-8°C
Computed Properties
Molecular Weight:237.26
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.090211983
Monoisotopic Mass:237.090211983
Topological Polar Surface Area:57.8
Heavy Atom Count:18
Complexity:301
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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