Carboxyethylgermanium sesquioxide
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Carboxyethylgermanium sesquioxide
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CAS No:
12758-40-6
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Formula:
C6H10Ge2O7
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Chemical Name:
Carboxyethylgermanium sesquioxide
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Synonyms:
Propanoic acid,3,3′-(1,3-dioxo-1,3-digermoxanediyl)bis-;3,3′-(1,3-Dioxo-1,3-digermoxanediyl)bis[propanoic acid];Carboxyethylgermanium sesquioxide;2-(Carboxyethyl)germanium sesquioxide;Ge 132;SK 818;Proxigermanium;β-Carboxyethylgermanium sesquioxide;Arlamol GEO;Rapagermanium;Serocion;Repagermanium;NSC 267004;3-[[2-Carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid;27031-31-8;31434-91-0;69992-83-2;83172-76-3;122402-75-9;1576423-70-5
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CAS No:
Description
Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium a
Propagermanium is an organogermanium compound.
Carboxyethylgermanium sesquioxide Basic Attributes
339.42
339.42
235-800-0
267004
DTXSID9065316
2934999090
Characteristics
118
0.01480
270 °C (decomp)
Slightly soluble in water.
LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)
Safety Information
2
36/37/38
26-36/37/39
UA2459750
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons. (See all compounds classified as Interferon Inducers.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
3-oxygermylpropionic acid polymer
Carboxyethylgermanium sesquioxide Use and Manufacturing
antifungal and antiseptic
Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis-: ACTIVE
Human drugs -> Rare disease (orphan)|Cosmetics -> Skin conditioning
Computed Properties
Molecular Weight:339.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:339.8859062
Monoisotopic Mass:341.8850082
Topological Polar Surface Area:118
Heavy Atom Count:15
Complexity:259
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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Carboxyethylgermanium sesquioxide
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