4-broMo-6-Methylpyridin-2-ol

4-hydroxy-6-methylpyridin-2(1H)-one (500 mg, 4.00 mmol) was mixed with phosphoryl bromide (881 mg, 3.07 mmol) and DMF (1.8 mL) was added. The reaction mixture was heated at 110 4-hydroxy-6-methylpyridin-2(1H)-one (500 mg, 4.00 mmol) was mixed with phosphoryl bromide (881 mg, 3.07 mmol) and DMF (1.8 mL) was added. The reaction mixture was heated at 110 0 After 5 mm, more DMF (1.8 mL) was added and the reaction was heated at 110 00 for 1 h. The reaction was cooled down and ice cold water was carefully added, followed by solid sodium bicarbonate until pH reached 7. The precipitate was filtered, rinced with cold water and let dry under air to give the title compound (520 mg, 2.77 mmol, 90percent).

Molecular Weight:188.02
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:186.96328
Monoisotopic Mass:186.96328
Topological Polar Surface Area:29.1
Heavy Atom Count:9
Complexity:205
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes