5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
-
5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
structure -
-
CAS No:
773873-77-1
-
Formula:
C10H8BrNO2
-
Chemical Name:
5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
-
Synonyms:
1H-Indole-3-carboxylicacid,5-broMo-,Methylester;Methyl 5-BroMoindole-3-carboxylate;5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER;METHYL 5-BROMO-1H-INDOLE-3-CARBOXYLATE;RARECHEM AL BF 0374
-
CAS No:
5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER Use and Manufacturing
General procedure: To a solution of compounds 21(b-c) (1 equiv) in MeOH, a solution of KOH in water was added. The reaction mixture was refluxed for 3 h. The solvents were removed under reduced pressure, the residue was partitioned between EtOAc and 1 N aq. HCl and the layers were separated. The aqueous layer was washed with EtOAc (3×) and the combined organic phases were washed with brine (1×), dried over anhydrous Na2SO4, filtered and concentrated to near dryness. The crude residue was purified by silica gel flash column chromatography eluted with mixtures of MeOH in dichloromethane to afford the corresponding methyl esters 22(b-c).General procedure: 4 g of 5-substituted indole- 3- carboxylic acids was dissolved in 10 volumes(400 mL) of methanol and catalytic amount of conc.H
Computed Properties
Molecular Weight:254.08
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:252.97384
Monoisotopic Mass:252.97384
Topological Polar Surface Area:42.1
Heavy Atom Count:14
Complexity:234
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
Cyclopentanecarboxylic acid, 2-(hydroxyimino)-, methyl ester (9CI)
170016-09-8
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
CYCLOPENTYL-CARBAMIC ACID PHENYL ESTER
58713-31-8
-
Cysteine, 2-methyl-, methyl ester (9CI) Formula
778548-47-3
-
D-Glucuronal 3,4-Diacetate Methyl Ester Formula
34296-99-6
-
2'-Deoxy-N-trimethylsilyl-3'-O-trimethylsilylcytidine 5'-phosphoric acid bis(trimethylsilyl) ester Formula
32645-72-0
-
4,6-Dichloro-1H-indole-2,3-dicarboxylic acid diethyl ester Structure
146012-24-0
-
2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester Structure
1154228-17-7
-
What is Dibenzoic acid 2-ethylhexamethylene ester
25724-54-3
-
What is 1,4-DIBENZYL-7-PHENYL-6-THIOXO-1,4,7-TRIAZA-SPIRO[4.4]NON-8-ENE-9-CARBOXYLIC ACID ETHYL ESTER
885722-38-3
5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
SDSRequest for Quotation