3-Bromo-4-Iodopyridine
-
3-Bromo-4-Iodopyridine
structure -
-
CAS No:
89167-19-1
-
Formula:
C5H3BrIN
-
Chemical Name:
3-Bromo-4-Iodopyridine
-
Synonyms:
3-bromo-4-iodopyridine;Pyridine, 3-bromo-4-iodo-;MFCD11110263;ACMC-209qyv;SCHEMBL14894420;CTK5G2583;KS-00000OQJ;DTXSID30680551;ANW-39221;BBL101503
-
CAS No:
3-Bromo-4-Iodopyridine Use and Manufacturing
Diisopropyl amine (1.2 g, 11.8 mmol) in anhydrous THF (50 ml) was cooled to - 78C and BuLi in hexanes (11.8 mmol) was added drop wise. The reaction was stirred for 30 minutes at -78C and neat 3-bromopyridine (2.06 g, 13.04 mmol) was added and stirred for a further 1 hr. A solution of iodine (6.02 g, 23.7 mmol) in THF (50 ml) was cannulated and the reaction stirred for 3 hrs at -78C. The reaction was quenched to a solution of EtOAc and sodium bisulfite (10% wt). The organics were washed with water, brine then dried and product isolated from 4:1 Hexanes and EtOAc as an off white solid. LC-MS m/z: 283 [M+l]
Computed Properties
Molecular Weight:283.89
XLogP3:2.2
Hydrogen Bond Acceptor Count:1
Exact Mass:282.84936
Monoisotopic Mass:282.84936
Topological Polar Surface Area:12.9
Heavy Atom Count:8
Complexity:78.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
