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Cyclic ADP-ribose

Cyclic ADP-ribose structure

Cyclic ADP-ribose 

structure
  • CAS No:

    119340-53-3

  • Formula:

    C15H21N5O13P2

  • Chemical Name:

    Cyclic ADP-ribose

  • Synonyms:

    Adenosine 5′-(trihydrogen diphosphate),1-β-D-ribofuranosyl-,intramol. P′,5′′-ester;cADPR;cAPD ribose;Cyclic ADP-ribose;143822-66-6;150155-83-2;1018828-36-8

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.


Cyclic ADP-ribose is a cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors. It has a role as a ryanodine receptor agonist and a metabolite. It is a cyclic purine nucleotide and a nucleotide-sugar. It derives from an ADP-D-ribose. It is a conjugate acid of a cyclic ADP-ribose(2-).|A pyridine nucleotide that mobilizes CALCIUM. It is synthesized from nicotinamide adenine dinucleotide (NAD) by ADP RIBOSE CYCLASE.

Cyclic ADP-ribose Basic Attributes

541.3

541.30

Q780BR06V8

Characteristics

259

-5.7

2.57±0.1 g/cm3(Predicted)

934.8±75.0 °C(Predicted)

519.1ºC

1.959

-20°C

Safety Information

NONH for all modes of transport

3

36/37/38

26-36

Xi

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Adenosine Diphosphate Ribose, Cyclic

Computed Properties

Molecular Weight:541.30
XLogP3:-5.7
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:16
Exact Mass:541.06110974
Monoisotopic Mass:541.06110974
Topological Polar Surface Area:259
Heavy Atom Count:35
Complexity:989
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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