4-bromo-2,6-dichloropyridine
-
4-bromo-2,6-dichloropyridine
structure -
-
CAS No:
98027-80-6
-
Formula:
C5H2BrCl2N
-
Chemical Name:
4-bromo-2,6-dichloropyridine
-
Synonyms:
4-bromo-2,6-dichloropyridine;4-Bromo-2,6-dichloropyridine 98%;4-Bromo-2,6-dichloropyridine98%;4-Bromo-2,6-dichloropyridine≥ 98% (HPLC)
- Categories:
-
CAS No:
Safety Information
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501
H302
|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
4-bromo-2,6-dichloropyridine Use and Manufacturing
4-bromo-2, 6-dichloropyridineTo a suspension of copper (II) bromide (8.2 g) in acetonitrile was added t-butylnitrile (5.5 mL) at O0C 4-amino-2, 6-dichloropyridne (5.0 g) in acetonitrile. The mixture slowly warmed to room temperature and stirred for an additional 12 h. The mixture was poured into 2N HCl and extracted with ethyl acetate, washed with brine, dried over magnesium sulfate, and concentrated. The title compound was recrystallized from toluene/hexanes (4.5 g).NaH (60% in mineral oil, 194 mg, 4.85 mmol) was added to a stirred solution of isopropyl alcohol (4 mL, 52.3 mmol) in THF (24 mL) at 0 C under N2 atmosphere. The mixture was stirred at room temperature for 1 h. In a 250 mL three-necked flask, nitrogen gas was introduced, and 0.02 mol of the raw material n-Butyllithium (38.8 mL, 97 mmol) was added dropwise to diisopropylamine (14.91 mL, 106 mmol) in THF (50 mL) at -78 C. The solution was stirred at -78 C for 0.5 h and at 0 C for 0.5 h. The crude pale yellow solution of lithium diisopropylamide was used in the next step without further purification. To a stirred and cooled (-78 C) solution of
Computed Properties
Molecular Weight:226.88
XLogP3:2.7
Hydrogen Bond Acceptor Count:1
Exact Mass:224.87477
Monoisotopic Mass:224.87477
Topological Polar Surface Area:12.9
Heavy Atom Count:9
Complexity:91
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 4-bromo-2,6-dichloropyridine
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8