 Home > Encyclopedia > Carubicin

Carubicin

Carubicin structure

CAS No:
50935-04-1
Formula:
C26H27NO10
Chemical Name:
Carubicin
Synonyms:
5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S,10S)-;5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-,(8S-cis)-;(8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione;Carminomicin I;Carminomycin I;Carubicin;Antibiotic R 588A;NSC 180024;NCI 180024;1795769-99-1
Categories:
Biochemical Engineering > Saccharides

Request for Quotation

Description

A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.

Carubicin Basic Attributes

Molecular Weight：

513.49

Exact Mass：

513.49

DSSTox ID：

DTXSID3022742

Characteristics

PSA：

197

XLogP3：

3.54

Density：

1.6±0.1 g/cm3

Boiling Point：

750.6±60.0 °C at 760 mmHg

Flash Point：

407.7±32.9 °C

Refractive Index：

1.727

Toxicity：

Oral-mouse LD50: 7.25 mg/kg; peritoneal-mouse LD50: 1.1 mg/kg

Flammability characteristics：

Thermal decomposition to emit toxic nitrogen oxide fumes

Safety Information

Storage features：

The warehouse is low-temperature, ventilated and dry; stored separately from food materials

Toxicity

Toxicity class：

most toxic

Drug Information

MeSH：

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)|Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)

MeSH Entry Terms：

Carminomicin

Carubicin Use and Manufacturing

Antineoplastic. .

Computed Properties

Molecular Weight:513.5
XLogP3:1.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:3
Exact Mass:513.16349606
Monoisotopic Mass:513.16349606
Topological Polar Surface Area:197
Heavy Atom Count:37
Complexity:944
Defined Atom Stereocenter Count:1
Undefined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Carubicin hydrochloride

52794-97-5
5'-deoxy-5'-thioinosine 5'-monophosphate

21959-63-7
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone

22003-30-1
5'-azacytidine5'-monophosphate Formula

2226-72-4
Decarboxylated AdoMet Formula

22365-13-5
2′-Deoxy-6-thioinosine Formula

2239-64-7
Quercetin 3-glucuronide Structure

22688-79-5
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one Structure

22882-02-6
What is Sucrose

57-50-1
What is C18Dihydroceramide

2304-80-5

Hot Searches: vanillin structure; red88.ag; uranium dioxide; magnesium fluoride; blastomyces dermatitidis; ferrous oxide

Guide of Carubicin

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

Carubicin

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.