 Home > Encyclopedia > 5-Chloro-1-(3H)-Isobenzofuranone

5-Chloro-1-(3H)-Isobenzofuranone

5-Chloro-1-(3H)-Isobenzofuranone structure

CAS No:
54109-03-4
Formula:
C8H5ClO2
Chemical Name:
5-Chloro-1-(3H)-Isobenzofuranone
Synonyms:
5-Chloro-1-(3H)-Isobenzofuranone;1(3H)-Isobenzofuranone, 5-chloro-;5-Chlorophthalide;NSC 49581
Categories:
Chemical Reagents > Organic Reagents

Request for Quotation

5-Chloro-1-(3H)-Isobenzofuranone Basic Attributes

Molecular Weight：

168.5771

Exact Mass：

167.99800

NSC Number：

49581

HScode：

2932209090

Characteristics

PSA：

26.3

XLogP3：

1.4

Density：

1.428g/cm3

Melting Point：

154-155℃

Boiling Point：

363.9°C at 760 mmHg

Flash Point：

205.9ºC

Refractive Index：

1.601

Safety Information

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

5-Chloro-1-(3H)-Isobenzofuranone Use and Manufacturing

General procedure: A magnetic stirring bar, 2-iodobenzyl alcohol (1a, 116.0 mg, 0.5 mmol), NEt3 (251.6 mg, 2.5 mmol), and MeCN (10 mL) were placed in a stainless steel autoclave equipped with an inserted Pyrex glass liner. The autoclave was closed, purged three times with carbon monoxide, pressurized with 65 atm of CO and then heated at 250 °C by salt bath with stirring for 16 h. After the reaction, excess CO was discharged at room temperature. The solvent was removed under reduced pressure, and the residue was purified by flash chromatography on silica gel (hexane/EtOAc = 3/1) to give 2a (60.4 mg, 91percent) as a white solid.

Computed Properties

Molecular Weight:168.57
XLogP3:1.4
Hydrogen Bond Acceptor Count:2
Exact Mass:167.9978071
Monoisotopic Mass:167.9978071
Topological Polar Surface Area:26.3
Heavy Atom Count:11
Complexity:181
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 5-Chloro-1-(3H)-Isobenzofuranone

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

5-Chloro-1-(3H)-Isobenzofuranone

CAS No.: 54109-03-4

Content: 99.00%

Inquiry
Compound Net Biotechnology Inc. Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

54109-03-4 5-chloro-3H-2-benzofuran-1-one

CAS No.: 54109-03-4

Grade: Industrial Grade

Content: 95%

Inquiry

Latest News on 5-Chloro-1-(3H)-Isobenzofuranone

Preparation and purification of zinc chloride

Learn More Other Chemicals

2-Bromophenacyl bromide, 90%

49851-55-0
1H-Indazol-7-ol

81382-46-9
6-Chloro-4-forMyl-nicotinic acid

1031433-06-3
3-Hydroxy-2,4,5-trifluorobenzoic acid Formula

116751-24-7
2-Methyl-1-heptene Formula

15870-10-7
1-(3,5-Dinitrophenyl)ethanone Formula

14401-75-3
α-Amino-3-bromobenzeneacetic acid Structure

79422-73-4
6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97% Structure

499770-85-3
What is Allyl methacrylate

96-05-9
What is ethyl 5-hydroxy-2-Methylnicotinate

60390-47-8

Hot Searches: thiamin mononitrate; what is boric acid; uranium oxide; nail dystrophy; aluminum phosphate formula; azoxystrobin

Guide of 5-Chloro-1-(3H)-Isobenzofuranone

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

5-Chloro-1-(3H)-Isobenzofuranone

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.