Cimetropium bromide
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Cimetropium bromide
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CAS No:
51598-60-8
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Formula:
C21H28NO4.Br
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Chemical Name:
Cimetropium bromide
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Synonyms:
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-,bromide (1:1),(1α,2β,4β,5α,7β)-;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-(cyclopropylmethyl)-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-,bromide,[7(S)-(1α,2β,4β,5α,7β)]-;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-,bromide,(1α,2β,4β,5α,7β)-;3-Oxa-9-azatricyclo[3.3.1.02,4]nonane,3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane deriv.;DA 3177;Cimetropium bromide;Alginor;N-Cyclopropylmethylscopolamine bromide
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CAS No:
Description
Cimetropium Bromide is a mAChR antagonist for long-term treatment of irritable bowel syndrome.
Drug Information
Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)
cimetropium
Cimetropium bromide Use and Manufacturing
The compound (I) and cyclopropyl bromide are refluxed in acetonitrile for 15 to 99 hours to obtain citonium bromide.
It can block the muscarinic receptors of visceral smooth muscle, so it has an anti-muscarinic effect and also relieves the spasm of smooth muscle. Used for gallstone colic, renal colic, gastrointestinal spasm pain, biliary and urinary tract spasm pain, dysmenorrhea, labor pain, etc.
Computed Properties
Molecular Weight:438.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:437.12017
Monoisotopic Mass:437.12017
Topological Polar Surface Area:59.1
Heavy Atom Count:27
Complexity:538
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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