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Home > Encyclopedia > 4-CHLORO-7-FLUORO-QUINAZOLINE

4-CHLORO-7-FLUORO-QUINAZOLINE

4-CHLORO-7-FLUORO-QUINAZOLINE structure

4-CHLORO-7-FLUORO-QUINAZOLINE 

structure

4-CHLORO-7-FLUORO-QUINAZOLINE Basic Attributes

182.58

182.004700

DTXSID10585358

2933990090

Characteristics

25.8

2.6

1.447

284.9±20.0 °C(Predicted)

126.1±21.8 °C

1.635

Safety Information

IRRITANT

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

4-CHLORO-7-FLUORO-QUINAZOLINE Use and Manufacturing

7-Fluoro-3H-quinazolin-4-one (8.2 g, 50 mmol) is heated at reflux in thionyl chloride (80 mL). Concentration affords the expected 4-Chloro-7-fluoro-quinazoline (9.1 g, quant).

Computed Properties

Molecular Weight:182.58
XLogP3:2.6
Hydrogen Bond Acceptor Count:3
Exact Mass:182.0047040
Monoisotopic Mass:182.0047040
Topological Polar Surface Area:25.8
Heavy Atom Count:12
Complexity:167
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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