 Home > Encyclopedia > Clofilium

Clofilium

Clofilium structure

CAS No:
68379-02-2
Formula:
C21H37ClN
Chemical Name:
Clofilium
Synonyms:
Benzenebutanaminium,4-chloro-N,N-diethyl-N-heptyl-;4-Chloro-N,N-diethyl-N-heptylbenzenebutanaminium;Clofilium
Categories:
Organic Chemistry > Amides

Request for Quotation

Description

Clofilium is an organic amino compound and a member of benzenes.

Clofilium Basic Attributes

Molecular Weight：

338.984

Exact Mass：

338.261

UNII：

847G178BMC

DSSTox ID：

DTXSID9048568

Characteristics

PSA：

XLogP3：

7.2

Drug Information

MeSH：

A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS. (See all compounds classified as Potassium Channel Blockers.)|Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

MeSH Entry Terms：

4-chloro-N,N-diethyl-N-heptylbenzenebutanaminium

Computed Properties

Molecular Weight:339.0
XLogP3:7.2
Rotatable Bond Count:13
Exact Mass:338.2614529
Monoisotopic Mass:338.2614529
Heavy Atom Count:23
Formal Charge:1
Complexity:267
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes