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Eberconazole

Eberconazole structure

Eberconazole 

structure
  • CAS No:

    128326-82-9

  • Formula:

    C18H14Cl2N2

  • Chemical Name:

    Eberconazole

  • Synonyms:

    1H-Imidazole,1-(2,4-dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-;1-(2,4-Dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1H-imidazole;Eberconazole

Description

Eberconazole is a new member of the azole class of antifungal agents, and it is indicated for the topical treatment of cutaneous fungal infections, including tinea corporis (ringworm of the body), tinea cruris (ringworm of the groin) and tinea pedis (athlete’s foot) infections.


1-(2,4-dichloro-10,11-dihydrodibenzo[a,d][7]annulen-5-yl)imidazole is a member of the class of dibenzannulenes that is 10,11-dihydrodibenzo[a,d][7]annulene carrying two chloro substituents at positions 2 and 4 as well as an imidazol-1-yl substituent at position 5. It is a member of imidazoles, an organochlorine compound and a dibenzannulene. It derives from a hydride of a dibenzo[a,d][7]annulene.

Eberconazole Basic Attributes

329.22

329.22

D - Dermatologicals

Characteristics

17.8

4.92620

1.35g/cm3

495ºC at 760mmHg

253.2ºC

1.679

Drug Information

1-(2,4-dichloro-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)-1H-imidazole

Computed Properties

Molecular Weight:329.2
XLogP3:4.9
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:328.0534038
Monoisotopic Mass:328.0534038
Topological Polar Surface Area:17.8
Heavy Atom Count:22
Complexity:391
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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