Dapiprazole hydrochloride
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Dapiprazole hydrochloride
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CAS No:
72822-13-0
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Formula:
C19H27N5.ClH
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Chemical Name:
Dapiprazole hydrochloride
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Synonyms:
1,2,4-Triazolo[4,3-a]pyridine,5,6,7,8-tetrahydro-3-[2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]-,hydrochloride (1:1);1,2,4-Triazolo[4,3-a]pyridine,5,6,7,8-tetrahydro-3-[2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]-,monohydrochloride;AF 2139;Dapiprazole hydrochloride;Rev-Eyes;Reversil;Glamidolo
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Categories:
Active Pharmaceutical Ingredients > Veterinary Raw Materials
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CAS No:
Description
Dapiprazole hydrochloride is a potent α-adrenergic blocking drug, which is used to reverse mydriasis after eye examination.(1) It inhibits amphetamine toxicity and alcohol and morphine withdrawal syndromes, produces sedation, blocks conditioned avoidance reflexes and reduces the response to noxious stimuli.(2) The orally administrated daily dose varied from 30 to 90 mg.
Characteristics
37.2
2.29040
1.2±0.1 g/cm3
206-207 °C
538.9°C at 760 mmHg
279.7±32.9 °C
1.658
LD50 in mice (mg/kg): 260 i.p. (Silvestrini)
Dapiprazole hydrochloride Use and Manufacturing
Dapiprazole is an alpha blocker. Dapiprazole is used in the reversal of diagnostic mydriasis.
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