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Desethyl Sildenafil

Desethyl Sildenafil structure

CAS No:
139755-91-2
Formula:
C20H26N6O4S
Chemical Name:
Desethyl Sildenafil
Synonyms:
Desethyl Sildenafil;5-[2-Hydroxy-5-(4-Methylpiperazinylsulphonyl)phenyl]1-Methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyraMidin-7-one;5-[2-Hydroxy-5-[[4-(Methyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one;Sildenafil EP IMpurity C;5-[2-Hydroxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;O-Desethyl sildenafil;Sildenafil impurity C
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Off-White Solid

Desethyl Sildenafil Basic Attributes

Molecular Weight：

446.52324

Exact Mass：

446.173615

UNII：

2TEH1FB1FX

Characteristics

PSA：

125

XLogP3：

0.95

Density：

1.5±0.1 g/cm3

Refractive Index：

1.707

Desethyl Sildenafil Use and Manufacturing

A metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.

Computed Properties

Molecular Weight:446.5
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:446.17362451
Monoisotopic Mass:446.17362451
Topological Polar Surface Area:129
Heavy Atom Count:31
Complexity:807
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes