Eperezolid
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Eperezolid
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CAS No:
165800-04-4
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Formula:
C18H23FN4O5
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Chemical Name:
Eperezolid
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Synonyms:
Acetamide,N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-;Acetamide,N-[[3-[3-fluoro-4-[4-(hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-,(S)-;Acetamide,N-[[(5S)-3-[3-fluoro-4-[4-(hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-;N-[[(5S)-3-[3-Fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide;U 100592;Eperezolid;PNU 100592
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CAS No:
Description
Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml).IC50 value: 1-4 mg/ml (MIC90, staphylococci) [1]Target: AntibioticEperezolid binds specifically to the 50S ribosomal subunit of Escherichia coli. The specific binding of eperezolid is dose dependent and is proportional to the ribosome concentrations. Scatchard analysis of the binding data rev
Characteristics
102
0.38670
1.370±0.06 g/cm3(Predicted)
174-176 °C
701.2±60.0 °C(Predicted)
377.9ºC
1.579
1.22E-20mmHg at 25°C
Drug Information
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)
eperezolid
Computed Properties
Molecular Weight:394.4
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:394.16524801
Monoisotopic Mass:394.16524801
Topological Polar Surface Area:102
Heavy Atom Count:28
Complexity:599
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes