Sodium trimetaphosphate

305.88500

305.84500

232-088-3

3IH6169RL0

DTXSID7052789

2835399000

177.51000

1.66560

White crystalline powder

2.49 g/cm³

588ºC

COLORLESS; INDEX OF REFRACTION: 1.433, 1.442, 1.446 /HEXAHYDRATE/

Soluble in water. Insoluble in alcohol.

Keep in a cool, dry location in a closed container.

Loses water on storage at 20 °C, becomes definitely anhydrous at 100 °C. /Hexahydrate/|Efflorescent, triclinic-rhombohedral prisms. Melting point 53 °C. Specific gravity 1.786. One gram dissolves in 4.5 ml water. Insol in alc. /Hexahydrate/

Ⅲ

3077

2

9

44

OY4025000

LOSES WATER ON STORAGE @ 20 DEG C /HEXAHYDRATE/

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Conditions of use: This substance is generally recognized as safe when used in accordance with good manufacturing practice.|Sodium metaphosphate used as a sequestrant in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

US BUREAU OF MINES TOXIC DUST MASK; PROTECTIVE GLOVES, CHEMICAL-TYPE GOGGLES, FULL-COVER CLOTHING.

If material /sodium phosphate, tribasic/ is involved in a fire: extinguish fire using agent suitable for type of surrounding fire (material itself does not burn or burns with difficulty). Keep material out of water sources and sewers, building dikes to contain flow as necessary.

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 454 kg. The toll free telephone number of the NRC is (800) 424-8802; In the Washington metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.6 (section IV. D.3.b).|Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

IDENTIFICATION AND USE: Trisodium trimetaphosphate exists as colorless efflorescent triclinic rhombohedral prisms. It is used in tooth polishing agents and used in synthetic dairy products. It is used in detergent processing, water softeners, sequesterants, emulsifiers, food additives, textile processing, and laundering. HUMAN EXPOSURE AND TOXICITY: Disodium salts such as the metaphosphates are toxic because of their excess alkalinity rather than from sodium excess. ANIMAL STUDIES: Rats fed diets containing this chemical, high doses had adverse effects on kidneys. Growth retardation was also observed in rats fed this chemical in diets.

LD50 Rat ip 3650 mg/kg

Cariostatic Agents|EXPTL USE: A 3-YR STUDY ON SCHOOL-AGE CHILDREN USING SODIUM TRIMETAPHOSPHATE AS A CHEWING GUM ADDITIVE PRODUCED REDUCTIONS IN PROXIMAL SURFACE DENTAL CARIES INCREMENTS AS COMPARED TO A NONCHEWING GUM GROUP. THE REDUCTIONS WERE 23.3% FOR THE SODIUM TRIMETAPHOSPHATE SUCROSE GUM GROUP & 47.6% FOR THE SODIUM TRIMETAPHOSPHATE NONSUGAR GROUP AS COMPARED TO THE NO-GUM GROUP. ... A MARGINAL EFFECT ON OVERALL CARIES INCREMENTS CAN BE ASCRIBED TO THE AGENT. THIS OVERALL EFFECT RESULTED FROM A SIGNIFICANT REDUCTION OF CARIES ON THE PROXIMAL SURFACES OF TEETH, ALTHOUGH OTHER SURFACES WERE NOT AS PROTECTED. ... THE LEVEL OF PROTECTION PROVIDED BY SODIUM TRIMETAPHOSPHATE IN THIS STUDY, OR BY DIETARY PHOSPHATES IN GENERAL, APPEARS SMALL RELATIVE TO OTHER CARIES-PREVENTING AGENTS, SUCH AS TOPICAL FLUORIDES.|SODIUM TRIMETAPHOSPHATE ADDED TO CHEWING GUM IS OF MARGINAL VALUE IN REDUCING DENTAL CARIES ON PROXIMAL SURFACES OF PERMANENT TEETH.

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)

... LITTLE, IF ANY, CYCLIC METAPHOSPHATE IS ABSORBED THRU INTESTINAL WALL WHEN ADMIN ORALLY. THE METAPHOSPHATES MUST FIRST BE HYDROLYZED TO TRIPOLYPHOSPHATE & NEXT TO ORTHOPHOSPHATE, WHICH THEN CAN BE ABSORBED.

Condensed phosphates (CP) used as food additives depressed the growth of 7 strains of Streptococcus mutans (serotype a-g) as assessed by disk diffusion methods. Minimal inhibitory concn (MIC) of condensed phosphates on Streptococcus mutans appeared to be related to their chelating capacity. The antibacterial action of condensed phosphates seemed largely bacteriostatic. Condensed phosphates depressed lactate production from glucose and sucrose by the cells of strain Kl-R. Condensed phosphates depressed insoluble glucan production from sucrose by the cells of Kl-R. The inhibition of sugar metabolism may be due to the interference of sugar transport into Streptococcus mutans induced by the chelation effects of condensed phosphates. Hamsters were inoculated orally with strain Kl-R and reared on the high-sucrose diet No 2000 supplemented with 2% (wt/wt) condensed phosphates for 60 days. Dietary supplements of condensed phosphates were associated with reduced caries activity and plaque formation.

... /SODIUM/ SALTS, SUCH AS METAPHOSPHATES, ARE TOXIC PROBABLY BECAUSE OF THEIR EXCESS ALKALINITY RATHER THAN FROM SIMPLE SODIUM EXCESS.

calcium trimetaphosphate

/Available from Monsanto Co as/ fine white powder, purified and technical grades ... purified grade meets FCC specifications on arsenic and heavy metals|TOOTHPASTES CONTAINING 0.5-95% SILICON DIOXIDE XEROGEL & 0.5-6% SODIUM TRIMETAPHOSPHATE ARE EFFECTIVE TOOTH POLISHING AGENTS.

All other chemical product and preparation manufacturing|Metaphosphoric acid (H3P3O9), sodium salt (1:3): ACTIVE|Stabilizing salts ... phosphates are used in imitation dairy products for one of the following purposes to: alter buffering capacity of the system; improve stability of the protein to calcium ions; improve the heat stability of the protein; minimize the age gelation of ultra-high temperature (UHT) processed imitation products; serve as emulsifying salts in imitation cheese manufacture; and modify the water-binding capacity of proteins and improve solubility ... .

It is suggested that dusts of trisodium phosphate be collected in an impinger containing distilled water which may then be titrated with a standard solution of sulfuric acid. They may also be analyzed for P2O3 content by precipitation of ammonium phosphomolybdate followed by redissolving in standard alkali & back-titrating with acid. Gravimetric procedures are also available, as are NMR spectroscopy & ion exchange chromatography. /Dodecahydrate/

Cosmetics -> Anticaking; Buffering; Chelating