(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
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CAS No:
147116-67-4
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Formula:
C32H40N2O
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Chemical Name:
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
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Synonyms:
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine;(2S-cis)-N-[[5-(1,1-DiMethylethyl)-2-Methoxyphenyl]Methyl]-2-(diphenylMethyl)-1-azabicyclo[2.2.2]octan-3-aMine;Maropitant;(2S,3S)-2-(Diphenylmethyl)-N-[2-methoxy-5-(2-methyl-2-propanyl)benzyl]quinuclidin-3-amine;1-Azabicyclo[2.2.2]octan-3-amine, N-[[5-(1,1-dimethylethyl)-2-methoxyphenyl]methyl]-2-(diphenylmethyl)-, (2S,3S)-;CJ-11972);Maropitant (CJ11,972;Maropitant-13C-d3Q: What is Maropitant-13C-d3 Q: What is the CAS Number of Maropitant-13C-d3
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CAS No:
Description
Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Basic Attributes
468.67
468.67
831-973-7
4XE2T9H4DH
Off-white to yellow
QA04AD90
Characteristics
1.11±0.1 g/cm3(Predicted)
572.6±50.0 °C(Predicted)
0-0Pa at 20-25℃
9.99±0.70(Predicted)
Store at -20°C
Safety Information
WGK 3
|Danger|H317 (66.67%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P260, P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P310, P314, P321, P333+P313, P337+P313, P363, P391, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Tablets Dogs:For the prevention of nausea induced by chemotherapy.For the prevention of vomiting induced by motion sickness.For the prevention and treatment of vomiting, in conjunction with Cerenia solution for injection and in combination with other supportive measures.Solution for injectionDogs:For the treatment and prevention of nausea induced by chemotherapy.For the prevention of vomiting except that induced by motion sickness.For the treatment of vomiting, in combination with other supportive measures.For the prevention of perioperative nausea and vomiting and improvement in recovery from general anaesthesia after use of the μ-opiate receptor agonist morphine.Cats:For the prevention of vomiting and the reduction of nausea, except that induced by motion sickness.For the treatment of vomiting, in combination with other supportive measures.|Dogs:For the treatment and prevention of nausea induced by chemotherapyFor the prevention of vomiting except that induced by motion sicknessFor the treatment of vomiting, in combination with other supportive measuresFor the prevention of perioperative nausea and vomiting and improvement in recovery from general anaesthesia after use of the μ-opiate receptor agonist morphineCats:For the prevention of vomiting and the reduction of nausea, except that induced by motion sicknessFor the treatment of vomiting, in combination with other supportive measures.
Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)
(2S,2S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine citrate monohydrate
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Use and Manufacturing
Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.
Veterinary drugs -> Cerenia -> EMA Drug Category|Alimentary tract and metabolism -> Veterinary pharmacotherapeutic group|Veterinary drugs -> Prevomax -> EMA Drug Category|Alimentary tract and metabolism, Other antiemetics -> Veterinary pharmacotherapeutic group|Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
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