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N-ACRYLOXYSUCCINIMIDE

N-ACRYLOXYSUCCINIMIDE structure

CAS No:
38862-24-7
Formula:
C7H7NO4
Chemical Name:
N-ACRYLOXYSUCCINIMIDE
Synonyms:
N-ACRYLOXYSUCCINIMIDE;ACRYLIC ACID N-HYDROXY-SUCCINIMIDE ESTER;AKOS MSC-0123;1-[(1-OXO-2-PROPENYL)OXY]-2,5-PYRROLIDINEDIONE;1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE;N-Acryloxysuccinimide (NAS);N-succinimidyl acrylate;Acrylic acid 2,5-dioxo-1-pyrrolidinyl ester
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

yellow crystals and chunks

N-ACRYLOXYSUCCINIMIDE Basic Attributes

Molecular Weight：

169.13

Exact Mass：

169.03750770

Color/Form：

Yellow

HScode：

29251900

Characteristics

PSA：

63.68000

XLogP3：

-0.28250

Appearance：

White powder

Density：

1.4523 (rough estimate)

Melting Point：

69 °C

Boiling Point：

298.4°C (rough estimate)

Flash Point：

105.8ºC

Refractive Index：

1.5500 (estimate)

Storage Conditions：

2-8ºC

Critical Temperature & Pressure：

2-8°C

Safety Information

wgk germany：

hazard class code：

safety instructions：

36-26-37/39

Marks：

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

36/37/38-40-48/20/22-36-22

GHS Classification：

|Warning|H302 (92.68%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501|Aggregated GHS information provided by 41 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

N-succinimidyl acrylate

N-ACRYLOXYSUCCINIMIDE Use and Manufacturing

sulfhydryl reactive cross-linking reagent affording sulfides and HI, can subsequently be radio-iodinated, the phenylazide function can then be photo-activated with long wavelength UV light to couple with another molecule

Acrylic acidN-hydroxysuccinimide ester (NAS) is a general acrylating agent that is used in the synthesis of:Acrylated hyaluronic acid (HA) hydrogel for bone regeneration applications.Injectable, biodegradable, and thermosensitive copolymers for tissue engineering.Imidazole-based biocompatible, aqueous quantum dots (QDs).

Computed Properties

Molecular Weight:169.13
XLogP3:-0.2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:169.03750770
Monoisotopic Mass:169.03750770
Topological Polar Surface Area:63.7
Heavy Atom Count:12
Complexity:242
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Acrylic acid N-hydroxysuccinimide ester

CAS No.: 38862-24-7

Content: 99.00%

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