TXB2
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TXB2
structure -
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CAS No:
54397-85-2
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Formula:
C20H34O6
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Chemical Name:
TXB2
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Synonyms:
5-Heptenoic acid,7-[(2R,3S,4S)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-,(5Z)-;Thromboxa-5,13-dien-1-oic acid,9,11,15-trihydroxy-,(5Z,9α,13E,15S)-;5-Heptenoic acid,7-[(2R,3S,4S)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-,(5Z)-;(5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-5-heptenoic acid;8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic acid hemiacetal;Thromboxane B2;TXB2
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CAS No:
Description
Solid
Thromboxane B2 is a member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It has a role as a human metabolite and a mouse metabolite. It is a conjugate acid of a thromboxane B2(1-).|A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).
Characteristics
95-96°
202.08 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|194.44 Ų [M-H]- [CCS Type: DT, Method: stepped-field]
Safety Information
3
63-52/53-34-32-23/24/25-5
22-36-45-36/37/39-26
Xn,T
|Warning|H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|P201, P202, P281, P308+P313, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.
TXB2 Use and Manufacturing
TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.
Fatty Acyls [FA] -> Eicosanoids [FA03] -> Thromboxanes [FA0303]
Computed Properties
Molecular Weight:370.5
XLogP3:2.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:370.23553880
Monoisotopic Mass:370.23553880
Topological Polar Surface Area:107
Heavy Atom Count:26
Complexity:448
Defined Atom Stereocenter Count:4
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of TXB2
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![South Africa]()
ZA
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Business licensedDistributor Supplier of Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid,Sodium Hydrosulfide,Acetic Acid Glacial,Trichloroisocyanuric Acid 90%,Hydrogen Peroxide,Calcium Carbide,Phosphoric Acid,Linear Alkylbenzene Sulfonic Acid,Sulphuric Acid,Ethanol 96%,Sodium BicarbonateInquiryCAS No.: 54397-85-2Grade: Industrial GradeContent: 99%
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